LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 PIK-93
0.04
uM
LJP5
 72
hr
 1334 4133 4033 1.0247 1.0302
BT-20 PIK-93
0.12
uM
LJP5
 72
hr
 1334 4135 4033 1.0257 1.0322
BT-20 PIK-93
0.37
uM
LJP5
 72
hr
 1334 4274 4033 1.0600 1.0745
BT-20 PIK-93
1.11
uM
LJP5
 72
hr
 1334 4128 4033 1.0242 1.0306
BT-20 PIK-93
3.33
uM
LJP5
 72
hr
 1334 3344 4033 0.8296 0.7792
BT-20 PIK-93
10
uM
LJP5
 72
hr
 1334 1431 4033 0.3550 0.0447
BT-20 Dactolisib
0.04
uM
LJP5
 72
hr
 1334 1982 4033 0.4920 0.2819
BT-20 Dactolisib
0.12
uM
LJP5
 72
hr
 1334 1715 4033 0.4260 0.1707
BT-20 Dactolisib
0.37
uM
LJP5
 72
hr
 1334 1463 4033 0.3631 0.0594
BT-20 Dactolisib
1.11
uM
LJP5
 72
hr
 1334 1371 4033 0.3402 0.0172
BT-20 Dactolisib
3.33
uM
LJP5
 72
hr
 1334 1375 4033 0.3411 0.0187
BT-20 Dactolisib
10
uM
LJP5
 72
hr
 1334 1437 4033 0.3569 0.0480
BT-20 Alpelisib
0.04
uM
LJP5
 72
hr
 1334 4126 4033 1.0234 1.0293
BT-20 Alpelisib
0.12
uM
LJP5
 72
hr
 1334 4100 4033 1.0166 1.0204
BT-20 Alpelisib
0.37
uM
LJP5
 72
hr
 1334 3247 4033 0.8050 0.7457
BT-20 Alpelisib
1.11
uM
LJP5
 72
hr
 1334 2990 4033 0.7411 0.6569
BT-20 Alpelisib
3.33
uM
LJP5
 72
hr
 1334 1664 4033 0.4132 0.1489
BT-20 Alpelisib
10
uM
LJP5
 72
hr
 1334 917 4033 0.2274 -0.2099
BT-20 GDC-0980
0.04
uM
LJP5
 72
hr
 1334 2403 4033 0.5962 0.4462
BT-20 GDC-0980
0.12
uM
LJP5
 72
hr
 1334 1553 4033 0.3855 0.0997
BT-20 GDC-0980
0.37
uM
LJP5
 72
hr
 1334 1192 4033 0.2957 -0.0685
BT-20 GDC-0980
1.11
uM
LJP5
 72
hr
 1334 994 4033 0.2467 -0.1684
BT-20 GDC-0980
3.33
uM
LJP5
 72
hr
 1334 897 4033 0.2228 -0.2204
BT-20 GDC-0980
10
uM
LJP5
 72
hr
 1334 857 4033 0.2129 -0.2422
BT-20 Mitoxantrone
0.04
uM
LJP5
 72
hr
 1334 1575 4033 0.3897 0.1056