LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD-6482 | 10 | uM | LJP5 | 72 | hr | 1235 | 1087 | 4267 | 0.2548 | -0.0694 |
| MCF7 | NU7441 | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4252 | 4267 | 0.9971 | 0.9971 |
| MCF7 | NU7441 | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4160 | 4267 | 0.9765 | 0.9738 |
| MCF7 | NU7441 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 4230 | 4267 | 0.9920 | 0.9913 |
| MCF7 | NU7441 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3783 | 4267 | 0.8868 | 0.8700 |
| MCF7 | NU7441 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 3178 | 4267 | 0.7458 | 0.6974 |
| MCF7 | NU7441 | 10 | uM | LJP5 | 72 | hr | 1235 | 1574 | 4267 | 0.3689 | 0.1448 |
| MCF7 | Barasertib | 10 | uM | LJP5 | 72 | hr | 1235 | 1550 | 4267 | 0.3632 | 0.1348 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3527 | 4267 | 0.8263 | 0.7970 |
| MCF7 | Vemurafenib | 0.37 | uM | LJP5 | 72 | hr | 1235 | 4319 | 4267 | 1.0135 | 1.0155 |
| MCF7 | Vemurafenib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 4159 | 4267 | 0.9760 | 0.9736 |
| MCF7 | Vemurafenib | 10 | uM | LJP5 | 72 | hr | 1235 | 3486 | 4267 | 0.8179 | 0.7876 |
| MCF7 | CP466722 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 4829 | 4267 | 1.1306 | 1.1406 |
| MCF7 | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3931 | 4267 | 0.9231 | 0.9119 |
| MCF7 | Crizotinib | 0.04 | uM | LJP5 | 72 | hr | 1235 | 3325 | 4267 | 0.7794 | 0.7387 |
| MCF7 | Enzastaurin | 10 | uM | LJP5 | 72 | hr | 1235 | 2312 | 4267 | 0.5424 | 0.4204 |
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 3061 | 4267 | 0.7180 | 0.6618 |
| MCF7 | Torin2 | 0.37 | uM | LJP5 | 72 | hr | 1235 | 1086 | 4267 | 0.2549 | -0.0692 |
| MCF7 | Crizotinib | 0.37 | uM | LJP5 | 72 | hr | 1235 | 2485 | 4267 | 0.5824 | 0.4780 |
| MCF7 | Barasertib | 0.04 | uM | LJP5 | 72 | hr | 1235 | 1732 | 4267 | 0.4070 | 0.2085 |
| MCF7 | Barasertib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 1597 | 4267 | 0.3747 | 0.1549 |
| MCF7 | Barasertib | 0.37 | uM | LJP5 | 72 | hr | 1235 | 1618 | 4267 | 0.3795 | 0.1630 |
| MCF7 | Barasertib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 1547 | 4267 | 0.3629 | 0.1343 |
| MCF7 | Pelitinib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 1938 | 4267 | 0.4541 | 0.2857 |
| MCF7 | Pelitinib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3706 | 4267 | 0.8687 | 0.8485 |