LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 WZ-4-145
10
uM
LJP6
 72
hr
 1657 2493 5383 0.4635 0.2719
MCF 10A WZ-4-145
10
uM
LJP6
 72
hr
 513 483 10473 0.0461 -0.0145
MCF 10A WZ-4-145
3.33
uM
LJP6
 72
hr
 513 4150 10473 0.3961 0.6162
Hs 578T WZ-4-145
10
uM
LJP6
 72
hr
 929 1275 3216 0.3965 0.1933
Hs 578T WZ-4-145
3.33
uM
LJP6
 72
hr
 929 1878 3216 0.5840 0.4812
Hs 578T WZ-4-145
1.11
uM
LJP6
 72
hr
 929 1990 3216 0.6189 0.5301
Hs 578T WZ-4-145
0.37
uM
LJP6
 72
hr
 929 2152 3216 0.6692 0.5982
Hs 578T WZ-4-145
0.12
uM
LJP6
 72
hr
 929 2364 3216 0.7350 0.6842
MCF 10A WZ-4-145
1.11
uM
LJP6
 72
hr
 513 5529 10473 0.5277 0.7256
MCF 10A WZ-4-145
0.37
uM
LJP6
 72
hr
 513 8239 10473 0.7867 0.8927
MCF 10A WZ-4-145
0.12
uM
LJP6
 72
hr
 513 9065 10473 0.8657 0.9347
MCF 10A WZ-4-145
0.04
uM
LJP6
 72
hr
 513 8831 10473 0.8433 0.9232
Hs 578T WZ-4-145
0.04
uM
LJP6
 72
hr
 929 2380 3216 0.7398 0.6902
BT-20 XL147
0.04
uM
LJP5
 72
hr
 1657 5818 5588 1.0412 1.0466
SK-BR-3 XL147
0.04
uM
LJP5
 72
hr
 1476 4230 3772 1.1217 1.1770
SK-BR-3 XL147
0.12
uM
LJP5
 72
hr
 1476 4313 3772 1.1433 1.2076
SK-BR-3 XL147
0.37
uM
LJP5
 72
hr
 1476 4284 3772 1.1358 1.1969
SK-BR-3 XL147
1.11
uM
LJP5
 72
hr
 1476 4479 3772 1.1871 1.2687
SK-BR-3 XL147
3.33
uM
LJP5
 72
hr
 1476 4341 3772 1.1507 1.2181
SK-BR-3 XL147
10
uM
LJP5
 72
hr
 1476 2821 3772 0.7481 0.6136
MCF7 XL147
0.04
uM
LJP5
 72
hr
 1235 4765 4267 1.1172 1.1282
MCF 10A XL147
0.12
uM
LJP5
 72
hr
 513 10166 10362 0.9807 0.9906
MCF7 XL147
0.12
uM
LJP5
 72
hr
 1235 4394 4267 1.0301 1.0337
MCF7 XL147
0.37
uM
LJP5
 72
hr
 1235 4542 4267 1.0654 1.0727
MCF7 XL147
1.11
uM
LJP5
 72
hr
 1235 4461 4267 1.0484 1.0518