LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | GDC-0980 | 0.37 | uM | LJP5 | 72 | hr | 513 | 967 | 10362 | 0.0933 | 0.1567 |
MCF 10A | GDC-0980 | 1.11 | uM | LJP5 | 72 | hr | 513 | 641 | 10362 | 0.0619 | 0.0506 |
MCF 10A | GDC-0980 | 3.33 | uM | LJP5 | 72 | hr | 513 | 603 | 10362 | 0.0583 | 0.0380 |
MCF 10A | GDC-0980 | 10 | uM | LJP5 | 72 | hr | 513 | 572 | 10362 | 0.0552 | 0.0241 |
MCF 10A | Mitoxantrone | 0.04 | uM | LJP5 | 72 | hr | 513 | 1036 | 10362 | 0.1000 | 0.1759 |
MCF 10A | Mitoxantrone | 0.04 | uM | LJP6 | 72 | hr | 513 | 907 | 10473 | 0.0867 | 0.1399 |
MCF 10A | Mitoxantrone | 0.12 | uM | LJP5 | 72 | hr | 513 | 662 | 10362 | 0.0639 | 0.0533 |
MCF 10A | Mitoxantrone | 0.12 | uM | LJP6 | 72 | hr | 513 | 690 | 10473 | 0.0659 | 0.0694 |
MCF 10A | Mitoxantrone | 0.37 | uM | LJP5 | 72 | hr | 513 | 555 | 10362 | 0.0536 | 0.0166 |
MCF 10A | Mitoxantrone | 0.37 | uM | LJP6 | 72 | hr | 513 | 552 | 10473 | 0.0527 | 0.0165 |
MCF 10A | Mitoxantrone | 1.11 | uM | LJP5 | 72 | hr | 513 | 387 | 10362 | 0.0373 | -0.0633 |
MCF 10A | Mitoxantrone | 1.11 | uM | LJP6 | 72 | hr | 513 | 458 | 10473 | 0.0438 | -0.0267 |
MCF 10A | Mitoxantrone | 3.33 | uM | LJP5 | 72 | hr | 513 | 371 | 10362 | 0.0358 | -0.0722 |
MCF 10A | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 513 | 407 | 10473 | 0.0389 | -0.0529 |
MCF 10A | Mitoxantrone | 10 | uM | LJP5 | 72 | hr | 513 | 403 | 10362 | 0.0389 | -0.0545 |
MCF 10A | Mitoxantrone | 10 | uM | LJP6 | 72 | hr | 513 | 464 | 10473 | 0.0443 | -0.0231 |
MCF 10A | Radicicol | 0.04 | uM | LJP5 | 72 | hr | 513 | 6621 | 10362 | 0.6390 | 0.8035 |
MCF 10A | Radicicol | 0.04 | uM | LJP6 | 72 | hr | 513 | 6388 | 10473 | 0.6099 | 0.7849 |
MCF 10A | Radicicol | 0.12 | uM | LJP5 | 72 | hr | 513 | 1750 | 10362 | 0.1692 | 0.3232 |
MCF 10A | Radicicol | 0.12 | uM | LJP6 | 72 | hr | 513 | 1851 | 10473 | 0.1768 | 0.3407 |
MCF 10A | Radicicol | 0.37 | uM | LJP5 | 72 | hr | 513 | 794 | 10362 | 0.0767 | 0.1045 |
MCF 10A | Radicicol | 0.37 | uM | LJP6 | 72 | hr | 513 | 841 | 10473 | 0.0803 | 0.1191 |
MCF 10A | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 513 | 720 | 10362 | 0.0696 | 0.0794 |
MCF 10A | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 513 | 742 | 10473 | 0.0709 | 0.0843 |
MCF 10A | Radicicol | 3.33 | uM | LJP5 | 72 | hr | 513 | 638 | 10362 | 0.0617 | 0.0493 |