LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A OSI-027
3.33
uM
LJP6
 72
hr
 513 1101 10473 0.1052 0.1917
MCF 10A OSI-027
10
uM
LJP6
 72
hr
 513 838 10473 0.0800 0.1175
MCF 10A WYE-125132
0.12
uM
LJP6
 72
hr
 513 1471 10473 0.1404 0.2736
MCF 10A WYE-125132
0.37
uM
LJP6
 72
hr
 513 1303 10473 0.1245 0.2383
MCF 10A Seliciclib
0.04
uM
LJP5
 72
hr
 513 10313 10362 0.9953 0.9978
MCF 10A Seliciclib
0.12
uM
LJP5
 72
hr
 513 9976 10362 0.9629 0.9824
MCF 10A Seliciclib
1.11
uM
LJP5
 72
hr
 513 9610 10362 0.9278 0.9654
MCF 10A Seliciclib
3.33
uM
LJP5
 72
hr
 513 8627 10362 0.8327 0.9169
MCF 10A AT-7519
0.12
uM
LJP6
 72
hr
 513 7852 10473 0.7495 0.8710
MCF 10A AT-7519
0.37
uM
LJP6
 72
hr
 513 995 10473 0.0950 0.1636
MCF 10A AT-7519
3.33
uM
LJP6
 72
hr
 513 665 10473 0.0636 0.0613
MCF 10A AT-7519
10
uM
LJP6
 72
hr
 513 482 10473 0.0461 -0.0150
MCF 10A AZD7762
1.11
uM
LJP6
 72
hr
 513 1722 10473 0.1645 0.3189
MCF 10A AZD7762
3.33
uM
LJP6
 72
hr
 513 936 10473 0.0894 0.1480
MCF 10A AZD8055
0.04
uM
LJP6
 72
hr
 513 2503 10473 0.2388 0.4339
MCF 10A AZD8055
0.12
uM
LJP6
 72
hr
 513 1215 10473 0.1160 0.2178
MCF 10A AZD8055
3.33
uM
LJP6
 72
hr
 513 927 10473 0.0885 0.1425
MCF 10A AZD8055
10
uM
LJP6
 72
hr
 513 840 10473 0.0802 0.1194
MCF 10A Sorafenib
0.12
uM
LJP6
 72
hr
 513 10401 10473 0.9931 0.9965
MCF 10A Sorafenib
0.37
uM
LJP6
 72
hr
 513 10330 10473 0.9863 0.9936
MCF 10A CP466722
0.12
uM
LJP5
 72
hr
 513 10964 10362 1.0581 1.0262
MCF 10A CP466722
0.37
uM
LJP5
 72
hr
 513 10725 10362 1.0350 1.0159
MCF 10A CP466722
3.33
uM
LJP5
 72
hr
 513 9517 10362 0.9184 0.9609
MCF 10A Barasertib
3.33
uM
LJP5
 72
hr
 513 1376 10362 0.1328 0.2553
MCF 10A Barasertib
1.11
uM
LJP5
 72
hr
 513 1268 10362 0.1224 0.2319