LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
SK-BR-3 XL147
3.33
uM
LJP5
 72
hr
 1476 4341 3772 1.1507 1.2181
Hs 578T SB590885
0.04
uM
LJP5
 72
hr
 929 3913 3237 1.2087 1.2219
Hs 578T Sorafenib
3.33
uM
LJP6
 72
hr
 929 3894 3216 1.2107 1.2253
SK-BR-3 Saracatinib
0.12
uM
LJP6
 72
hr
 1476 4158 3643 1.1448 1.2253
Hs 578T SB590885
3.33
uM
LJP5
 72
hr
 929 3939 3237 1.2167 1.2301
Hs 578T Sorafenib
0.37
uM
LJP6
 72
hr
 929 3923 3216 1.2199 1.2347
SK-BR-3 R406
1.11
uM
LJP6
 72
hr
 1476 4206 3643 1.1578 1.2443
SK-BR-3 PD173074
3.33
uM
LJP6
 72
hr
 1476 4220 3643 1.1605 1.2471
BT-20 Enzastaurin
10
uM
LJP5
 72
hr
 1657 6867 5588 1.2290 1.2497
SK-BR-3 Saracatinib
0.04
uM
LJP6
 72
hr
 1476 4233 3643 1.1657 1.2572
SK-BR-3 PD173074
1.11
uM
LJP6
 72
hr
 1476 4269 3643 1.1728 1.2634
SK-BR-3 XL147
1.11
uM
LJP5
 72
hr
 1476 4479 3772 1.1871 1.2687
SK-BR-3 PD173074
0.12
uM
LJP6
 72
hr
 1476 4293 3643 1.1784 1.2700
SK-BR-3 PD173074
0.04
uM
LJP6
 72
hr
 1476 4309 3643 1.1824 1.2748
Hs 578T Sorafenib
1.11
uM
LJP6
 72
hr
 929 4060 3216 1.2624 1.2779