LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Seliciclib
0.04
uM
LJP5
 72
hr
 1235 4831 4267 1.1327 1.1447
MCF7 Sigma A6730
3.33
uM
LJP5
 72
hr
 1235 2373 4267 0.5560 0.4399
MCF7 WH-4-025
0.04
uM
LJP5
 72
hr
 1235 4203 4267 0.9846 0.9821
MCF7 HG-5-113-01
0.04
uM
LJP5
 72
hr
 1235 3513 4267 0.8246 0.7956
MCF7 HG-5-113-01
0.12
uM
LJP5
 72
hr
 1235 2603 4267 0.6116 0.5180
MCF7 HG-5-113-01
0.37
uM
LJP5
 72
hr
 1235 1706 4267 0.4006 0.1983
MCF7 HG-5-113-01
1.11
uM
LJP5
 72
hr
 1235 1446 4267 0.3389 0.0915
MCF7 HG-5-113-01
3.33
uM
LJP5
 72
hr
 1235 1371 4267 0.3216 0.0600
MCF7 HG-5-113-01
10
uM
LJP5
 72
hr
 1235 883 4267 0.2073 -0.1712
MCF7 SB590885
0.04
uM
LJP5
 72
hr
 1235 4382 4267 1.0253 1.0258
MCF7 CP466722
0.04
uM
LJP5
 72
hr
 1235 4851 4267 1.1371 1.1490
MCF7 SB590885
0.37
uM
LJP5
 72
hr
 1235 4641 4267 1.0866 1.0935
MCF7 CP466722
0.12
uM
LJP5
 72
hr
 1235 4537 4267 1.0633 1.0695
MCF7 Seliciclib
1.11
uM
LJP5
 72
hr
 1235 3527 4267 0.8263 0.7970
MCF7 CP466722
0.37
uM
LJP5
 72
hr
 1235 4829 4267 1.1306 1.1406
MCF7 Neratinib
3.33
uM
LJP5
 72
hr
 1235 2031 4267 0.4761 0.3201
MCF7 CP466722
1.11
uM
LJP5
 72
hr
 1235 4687 4267 1.0985 1.1079
MCF7 Dasatinib
0.12
uM
LJP5
 72
hr
 1235 1273 4267 0.2988 0.0173
MCF7 CP466722
3.33
uM
LJP5
 72
hr
 1235 4230 4267 0.9910 0.9888
MCF7 Dasatinib
1.11
uM
LJP5
 72
hr
 1235 999 4267 0.2344 -0.1123
MCF7 CP466722
10
uM
LJP5
 72
hr
 1235 1972 4267 0.4623 0.2987
MCF7 Neratinib
0.04
uM
LJP5
 72
hr
 1235 3207 4267 0.7514 0.7040
MCF7 Neratinib
0.12
uM
LJP5
 72
hr
 1235 2830 4267 0.6631 0.5890
MCF7 PD184352
0.37
uM
LJP5
 72
hr
 1235 3401 4267 0.7967 0.7604
MCF7 PD184352
0.12
uM
LJP5
 72
hr
 1235 3911 4267 0.9172 0.9059