LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Vemurafenib
0.04
uM
LJP5
 72
hr
 1235 4219 4267 0.9908 0.9890
MCF7 Vemurafenib
0.12
uM
LJP5
 72
hr
 1235 4427 4267 1.0382 1.0428
MCF7 Vemurafenib
0.37
uM
LJP5
 72
hr
 1235 4319 4267 1.0135 1.0155
MCF7 Vemurafenib
1.11
uM
LJP5
 72
hr
 1235 4134 4267 0.9698 0.9664
MCF7 Vemurafenib
3.33
uM
LJP5
 72
hr
 1235 4159 4267 0.9760 0.9736
MCF7 Vemurafenib
10
uM
LJP5
 72
hr
 1235 3486 4267 0.8179 0.7876
MCF7 Enzastaurin
0.04
uM
LJP5
 72
hr
 1235 4036 4267 0.9475 0.9410
MCF7 Enzastaurin
0.12
uM
LJP5
 72
hr
 1235 4134 4267 0.9704 0.9669
MCF7 Enzastaurin
0.37
uM
LJP5
 72
hr
 1235 4352 4267 1.0209 1.0238
MCF7 Enzastaurin
1.11
uM
LJP5
 72
hr
 1235 3931 4267 0.9231 0.9119
MCF7 Enzastaurin
3.33
uM
LJP5
 72
hr
 1235 3734 4267 0.8768 0.8583
MCF7 Enzastaurin
10
uM
LJP5
 72
hr
 1235 2312 4267 0.5424 0.4204
MCF7 CP466722
10
uM
LJP5
 72
hr
 1235 1972 4267 0.4623 0.2987
MCF7 Seliciclib
0.12
uM
LJP5
 72
hr
 1235 4452 4267 1.0429 1.0455
MCF7 PD0325901
1.11
uM
LJP5
 72
hr
 1235 2435 4267 0.5703 0.4603
MCF7 Neratinib
0.04
uM
LJP5
 72
hr
 1235 3207 4267 0.7514 0.7040
MCF7 Geldanamycin
0.04
uM
LJP5
 72
hr
 1235 2274 4267 0.5332 0.4066
MCF7 Geldanamycin
0.37
uM
LJP5
 72
hr
 1235 1395 4267 0.3268 0.0695
MCF7 Geldanamycin
1.11
uM
LJP5
 72
hr
 1235 1371 4267 0.3216 0.0600
MCF7 Neratinib
0.12
uM
LJP5
 72
hr
 1235 2830 4267 0.6631 0.5890
MCF7 YM 201636
0.12
uM
LJP5
 72
hr
 1235 4254 4267 0.9964 0.9952
MCF7 CP724714
0.04
uM
LJP5
 72
hr
 1235 3247 4267 0.7619 0.7178
MCF7 YM 201636
1.11
uM
LJP5
 72
hr
 1235 2946 4267 0.6904 0.6255
MCF7 GSK1059615
10
uM
LJP5
 72
hr
 1235 768 4267 0.1803 -0.2331
MCF7 GSK1059615
3.33
uM
LJP5
 72
hr
 1235 1063 4267 0.2495 -0.0803