LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
SK-BR-3 Radicicol
3.33
uM
LJP5
 72
hr
 1476 1575 3772 0.4175 0.0484
SK-BR-3 Radicicol
3.33
uM
LJP6
 72
hr
 1476 1532 3643 0.4201 0.0252
SK-BR-3 Radicicol
10
uM
LJP5
 72
hr
 1476 1213 3772 0.3217 -0.1352
SK-BR-3 Radicicol
10
uM
LJP6
 72
hr
 1476 1124 3643 0.3113 -0.1876
SK-BR-3 Withaferin A
0.04
uM
LJP5
 72
hr
 1476 3835 3772 1.0169 1.0249
SK-BR-3 Withaferin A
0.04
uM
LJP6
 72
hr
 1476 3774 3643 1.0354 1.0527
SK-BR-3 Withaferin A
0.12
uM
LJP5
 72
hr
 1476 3448 3772 0.9137 0.8692
SK-BR-3 Withaferin A
0.12
uM
LJP6
 72
hr
 1476 3180 3643 0.8726 0.7997
SK-BR-3 Withaferin A
0.37
uM
LJP5
 72
hr
 1476 1592 3772 0.4222 0.0571
SK-BR-3 Withaferin A
0.37
uM
LJP6
 72
hr
 1476 1417 3643 0.3884 -0.0349
SK-BR-3 Withaferin A
1.11
uM
LJP5
 72
hr
 1476 1392 3772 0.3690 -0.0432
SK-BR-3 Withaferin A
1.11
uM
LJP6
 72
hr
 1476 1234 3643 0.3384 -0.1313
SK-BR-3 Withaferin A
3.33
uM
LJP5
 72
hr
 1476 829 3772 0.2199 -0.3472
SK-BR-3 Withaferin A
3.33
uM
LJP6
 72
hr
 1476 834 3643 0.2292 -0.3564
SK-BR-3 Withaferin A
10
uM
LJP5
 72
hr
 1476 940 3772 0.2493 -0.2838