LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Sorafenib | 0.37 | uM | LJP6 | 72 | hr | 1235 | 3908 | 4056 | 0.9638 | 0.9574 |
| MCF7 | Sorafenib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 3680 | 4056 | 0.9076 | 0.8897 |
| MCF7 | Sorafenib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 3446 | 4056 | 0.8503 | 0.8195 |
| MCF7 | Sorafenib | 10 | uM | LJP6 | 72 | hr | 1235 | 1645 | 4056 | 0.4061 | 0.1821 |
| MCF7 | AZD7762 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1544 | 4056 | 0.3810 | 0.1390 |
| MCF7 | AZD7762 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1310 | 4056 | 0.3230 | 0.0347 |
| MCF7 | AT-7519 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1396 | 4056 | 0.3443 | 0.0741 |
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1057 | 4056 | 0.2607 | -0.0870 |
| MCF7 | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1433 | 4056 | 0.3534 | 0.0904 |
| MCF7 | AZD7762 | 10 | uM | LJP6 | 72 | hr | 1235 | 765 | 4056 | 0.1887 | -0.2437 |
| MCF7 | AT-7519 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 834 | 4056 | 0.2059 | -0.2046 |
| MCF7 | AZD8055 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1307 | 4056 | 0.3227 | 0.0327 |
| MCF7 | HG-5-88-01 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 2639 | 4056 | 0.6514 | 0.5573 |
| MCF7 | AZD8055 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1319 | 4056 | 0.3253 | 0.0390 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 861 | 4056 | 0.2124 | -0.1898 |
| MCF7 | AZD8055 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1289 | 4056 | 0.3181 | 0.0251 |
| MCF7 | Alvocidib | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1126 | 4056 | 0.2776 | -0.0528 |
| MCF7 | Alvocidib | 0.12 | uM | LJP6 | 72 | hr | 1235 | 676 | 4056 | 0.1668 | -0.2966 |
| MCF7 | Alvocidib | 0.37 | uM | LJP6 | 72 | hr | 1235 | 694 | 4056 | 0.1712 | -0.2854 |
| MCF7 | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 1235 | 573 | 4056 | 0.1413 | -0.3613 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 1235 | 542 | 4056 | 0.1338 | -0.3813 |
| MCF7 | Alvocidib | 10 | uM | LJP6 | 72 | hr | 1235 | 512 | 4056 | 0.1258 | -0.4073 |
| MCF7 | GW843682X | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3022 | 4056 | 0.7449 | 0.6839 |
| MCF7 | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1616 | 4056 | 0.3977 | 0.1658 |
| MCF7 | JW-7-24-1 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 2410 | 4056 | 0.5943 | 0.4765 |