LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | CP724714 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 2084 | 3772 | 0.5526 | 0.2900 |
| SK-BR-3 | CP724714 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1595 | 3772 | 0.4230 | 0.0586 |
| SK-BR-3 | CP724714 | 10 | uM | LJP5 | 72 | hr | 1476 | 1297 | 3772 | 0.3440 | -0.0913 |
| SK-BR-3 | Alvocidib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1219 | 3643 | 0.3368 | -0.1356 |
| SK-BR-3 | Alvocidib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1225 | 3643 | 0.3381 | -0.1326 |
| SK-BR-3 | Seliciclib | 0.04 | uM | LJP5 | 72 | hr | 1476 | 4165 | 3772 | 1.1039 | 1.1507 |
| SK-BR-3 | Seliciclib | 0.12 | uM | LJP5 | 72 | hr | 1476 | 4001 | 3772 | 1.0607 | 1.0888 |
| SK-BR-3 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 1476 | 3292 | 3772 | 0.8728 | 0.8087 |
| SK-BR-3 | Seliciclib | 3.33 | uM | LJP5 | 72 | hr | 1476 | 2912 | 3772 | 0.7723 | 0.6524 |
| SK-BR-3 | AT-7519 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1759 | 3643 | 0.4832 | 0.1428 |
| SK-BR-3 | AT-7519 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 1424 | 3643 | 0.3915 | -0.0279 |
| SK-BR-3 | AT-7519 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 983 | 3643 | 0.2715 | -0.2680 |
| SK-BR-3 | AT-7519 | 10 | uM | LJP6 | 72 | hr | 1476 | 788 | 3643 | 0.2184 | -0.3826 |
| SK-BR-3 | AZD7762 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 1052 | 3643 | 0.2870 | -0.2365 |
| SK-BR-3 | AZD7762 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1004 | 3643 | 0.2744 | -0.2613 |
| SK-BR-3 | AZD8055 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 1566 | 3643 | 0.4308 | 0.0464 |
| SK-BR-3 | AZD8055 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 1473 | 3643 | 0.4058 | -0.0006 |
| SK-BR-3 | AZD8055 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 1322 | 3643 | 0.3635 | -0.0821 |
| SK-BR-3 | AZD8055 | 10 | uM | LJP6 | 72 | hr | 1476 | 1074 | 3643 | 0.2955 | -0.2183 |
| SK-BR-3 | Sorafenib | 0.12 | uM | LJP6 | 72 | hr | 1476 | 3294 | 3643 | 0.9060 | 0.8564 |
| SK-BR-3 | Sorafenib | 0.37 | uM | LJP6 | 72 | hr | 1476 | 3427 | 3643 | 0.9437 | 0.9173 |
| SK-BR-3 | CP466722 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 3985 | 3772 | 1.0566 | 1.0829 |
| SK-BR-3 | CP466722 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 3773 | 3772 | 1.0002 | 0.9996 |
| SK-BR-3 | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2171 | 3643 | 0.5976 | 0.3471 |
| SK-BR-3 | GW843682X | 0.04 | uM | LJP6 | 72 | hr | 1476 | 3249 | 3643 | 0.8925 | 0.8335 |