LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | WZ-4-145 | 10 | uM | LJP6 | 72 | hr | 1476 | 1150 | 3643 | 0.3155 | -0.1767 |
| SK-BR-3 | WZ3105 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 1114 | 3772 | 0.2953 | -0.1883 |
| SK-BR-3 | WZ3105 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1234 | 3772 | 0.3273 | -0.1242 |
| SK-BR-3 | WZ3105 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1182 | 3772 | 0.3135 | -0.1536 |
| SK-BR-3 | WZ3105 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1235 | 3772 | 0.3275 | -0.1238 |
| SK-BR-3 | WZ3105 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1189 | 3772 | 0.3153 | -0.1480 |
| SK-BR-3 | WZ3105 | 10 | uM | LJP5 | 72 | hr | 1476 | 1380 | 3772 | 0.3660 | -0.0488 |
| SK-BR-3 | XMD11-50 | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2726 | 3643 | 0.7503 | 0.6056 |
| SK-BR-3 | XMD11-50 | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2845 | 3643 | 0.7825 | 0.6580 |
| SK-BR-3 | XMD11-50 | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2620 | 3643 | 0.7215 | 0.5582 |
| SK-BR-3 | XMD11-50 | 1.11 | uM | LJP6 | 72 | hr | 1476 | 2480 | 3643 | 0.6813 | 0.4891 |
| SK-BR-3 | XMD11-50 | 3.33 | uM | LJP6 | 72 | hr | 1476 | 2122 | 3643 | 0.5854 | 0.3264 |
| SK-BR-3 | XMD11-50 | 10 | uM | LJP6 | 72 | hr | 1476 | 1647 | 3643 | 0.4533 | 0.0884 |
| SK-BR-3 | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 1476 | 2628 | 3643 | 0.7248 | 0.5645 |
| SK-BR-3 | XMD11-85h | 0.12 | uM | LJP6 | 72 | hr | 1476 | 2948 | 3643 | 0.8109 | 0.7044 |
| SK-BR-3 | XMD11-85h | 0.37 | uM | LJP6 | 72 | hr | 1476 | 2994 | 3643 | 0.8238 | 0.7253 |
| SK-BR-3 | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 1476 | 3011 | 3643 | 0.8292 | 0.7345 |
| SK-BR-3 | XMD11-85h | 3.33 | uM | LJP6 | 72 | hr | 1476 | 3082 | 3643 | 0.8485 | 0.7651 |
| SK-BR-3 | XMD11-85h | 10 | uM | LJP6 | 72 | hr | 1476 | 2332 | 3643 | 0.6420 | 0.4233 |
| SK-BR-3 | XMD16-144 | 0.04 | uM | LJP5 | 72 | hr | 1476 | 2078 | 3772 | 0.5510 | 0.2869 |
| SK-BR-3 | XMD16-144 | 0.12 | uM | LJP5 | 72 | hr | 1476 | 1397 | 3772 | 0.3702 | -0.0406 |
| SK-BR-3 | XMD16-144 | 0.37 | uM | LJP5 | 72 | hr | 1476 | 1478 | 3772 | 0.3919 | 0.0006 |
| SK-BR-3 | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 1476 | 1444 | 3772 | 0.3828 | -0.0165 |
| SK-BR-3 | XMD16-144 | 3.33 | uM | LJP5 | 72 | hr | 1476 | 1520 | 3772 | 0.4029 | 0.0212 |
| SK-BR-3 | XMD16-144 | 10 | uM | LJP5 | 72 | hr | 1476 | 1086 | 3772 | 0.2880 | -0.2035 |