LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Canertinib
0.04
uM
LJP6
 72
hr
 513 2411 10473 0.2300 0.4236
MCF 10A Canertinib
0.12
uM
LJP6
 72
hr
 513 1120 10473 0.1069 0.1955
MCF 10A Canertinib
0.37
uM
LJP6
 72
hr
 513 737 10473 0.0703 0.0861
MCF 10A Canertinib
1.11
uM
LJP6
 72
hr
 513 663 10473 0.0633 0.0605
MCF 10A Canertinib
3.33
uM
LJP6
 72
hr
 513 694 10473 0.0663 0.0714
MCF 10A Canertinib
10
uM
LJP6
 72
hr
 513 223 10473 0.0213 -0.1849
MCF 10A NVP-AEW541
0.04
uM
LJP5
 72
hr
 513 9731 10362 0.9390 0.9711
MCF 10A NVP-AEW541
0.12
uM
LJP5
 72
hr
 513 8816 10362 0.8505 0.9264
MCF 10A NVP-AEW541
0.37
uM
LJP5
 72
hr
 513 6000 10362 0.5783 0.7592
MCF 10A NVP-AEW541
1.11
uM
LJP5
 72
hr
 513 3345 10362 0.3225 0.5387
MCF 10A NVP-AEW541
3.33
uM
LJP5
 72
hr
 513 3020 10362 0.2914 0.5043
MCF 10A NVP-AEW541
10
uM
LJP5
 72
hr
 513 1146 10362 0.1106 0.2022
MCF 10A PHA-665752
0.04
uM
LJP5
 72
hr
 513 9929 10362 0.9580 0.9799
MCF 10A PHA-665752
0.12
uM
LJP5
 72
hr
 513 10091 10362 0.9738 0.9877
MCF 10A PHA-665752
0.37
uM
LJP5
 72
hr
 513 9740 10362 0.9398 0.9712
MCF 10A PHA-665752
1.11
uM
LJP5
 72
hr
 513 9599 10362 0.9261 0.9647
MCF 10A PHA-665752
3.33
uM
LJP5
 72
hr
 513 9651 10362 0.9313 0.9674
MCF 10A PHA-665752
10
uM
LJP5
 72
hr
 513 684 10362 0.0661 0.0614
MCF 10A PI103
0.04
uM
LJP6
 72
hr
 513 8242 10473 0.7871 0.8928
MCF 10A PI103
0.12
uM
LJP6
 72
hr
 513 3982 10473 0.3803 0.6003
MCF 10A PI103
0.37
uM
LJP6
 72
hr
 513 1481 10473 0.1414 0.2746
MCF 10A PI103
1.11
uM
LJP6
 72
hr
 513 1061 10473 0.1013 0.1789
MCF 10A PI103
3.33
uM
LJP6
 72
hr
 513 811 10473 0.0774 0.1105
MCF 10A PI103
10
uM
LJP6
 72
hr
 513 772 10473 0.0737 0.0984
MCF 10A Dovitinib
0.04
uM
LJP5
 72
hr
 513 9037 10362 0.8725 0.9377