LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A BI-2536
0.12
uM
LJP6
 72
hr
 513 846 10473 0.0808 0.1200
MCF 10A BI-2536
0.37
uM
LJP6
 72
hr
 513 889 10473 0.0849 0.1343
MCF 10A BI-2536
1.11
uM
LJP6
 72
hr
 513 797 10473 0.0762 0.1063
MCF 10A BI-2536
3.33
uM
LJP6
 72
hr
 513 740 10473 0.0706 0.0872
MCF 10A BI-2536
10
uM
LJP6
 72
hr
 513 760 10473 0.0726 0.0939
MCF 10A A443654
0.04
uM
LJP6
 72
hr
 513 4000 10473 0.3819 0.6023
MCF 10A A443654
0.12
uM
LJP6
 72
hr
 513 2023 10473 0.1932 0.3701
MCF 10A A443654
0.37
uM
LJP6
 72
hr
 513 692 10473 0.0661 0.0704
MCF 10A A443654
1.11
uM
LJP6
 72
hr
 513 445 10473 0.0425 -0.0324
MCF 10A A443654
3.33
uM
LJP6
 72
hr
 513 351 10473 0.0335 -0.0835
MCF 10A A443654
10
uM
LJP6
 72
hr
 513 415 10473 0.0397 -0.0489
MCF 10A SB590885
0.04
uM
LJP5
 72
hr
 513 10835 10362 1.0457 1.0206
MCF 10A SB590885
0.12
uM
LJP5
 72
hr
 513 10715 10362 1.0340 1.0153
MCF 10A SB590885
0.37
uM
LJP5
 72
hr
 513 10700 10362 1.0328 1.0148
MCF 10A SB590885
1.11
uM
LJP5
 72
hr
 513 10343 10362 0.9984 0.9990
MCF 10A SB590885
3.33
uM
LJP5
 72
hr
 513 9274 10362 0.8952 0.9493
MCF 10A SB590885
10
uM
LJP5
 72
hr
 513 4167 10362 0.4021 0.6208
MCF 10A Pictilisib
0.04
uM
LJP6
 72
hr
 513 5147 10473 0.4915 0.6984
MCF 10A Pictilisib
0.12
uM
LJP6
 72
hr
 513 3776 10473 0.3607 0.5817
MCF 10A Pictilisib
0.37
uM
LJP6
 72
hr
 513 2168 10473 0.2069 0.3906
MCF 10A Pictilisib
1.11
uM
LJP6
 72
hr
 513 1404 10473 0.1341 0.2602
MCF 10A Pictilisib
3.33
uM
LJP6
 72
hr
 513 1104 10473 0.1055 0.1915
MCF 10A Pictilisib
10
uM
LJP6
 72
hr
 513 704 10473 0.0672 0.0740
MCF 10A PD184352
0.04
uM
LJP5
 72
hr
 513 4620 10362 0.4460 0.6600
MCF 10A PD184352
0.12
uM
LJP5
 72
hr
 513 2900 10362 0.2802 0.4899