LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HG-6-64-01 | 0.04 | uM | LJP6 | 3 | M06 | 72 | hr | 1209 | 4406 | 4121 | 1.0691 | 1.0770 |
| MCF7 | HG-6-64-01 | 0.12 | uM | LJP6 | 1 | M05 | 72 | hr | 1209 | 3599 | 3823 | 0.9414 | 0.9286 |
| MCF7 | HG-6-64-01 | 0.12 | uM | LJP6 | 2 | M05 | 72 | hr | 1209 | 3937 | 4093 | 0.9617 | 0.9561 |
| MCF7 | HG-6-64-01 | 0.12 | uM | LJP6 | 3 | M05 | 72 | hr | 1209 | 4188 | 4121 | 1.0162 | 1.0183 |
| MCF7 | HG-6-64-01 | 0.37 | uM | LJP6 | 1 | M04 | 72 | hr | 1209 | 4077 | 3823 | 1.0664 | 1.0790 |
| MCF7 | HG-6-64-01 | 0.37 | uM | LJP6 | 2 | M04 | 72 | hr | 1209 | 4037 | 4093 | 0.9861 | 0.9842 |
| MCF7 | HG-6-64-01 | 0.37 | uM | LJP6 | 3 | M04 | 72 | hr | 1209 | 4443 | 4121 | 1.0781 | 1.0869 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 1 | M03 | 72 | hr | 1209 | 4002 | 3823 | 1.0468 | 1.0559 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 2 | M03 | 72 | hr | 1209 | 4145 | 4093 | 1.0125 | 1.0142 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 3 | M03 | 72 | hr | 1209 | 4376 | 4121 | 1.0618 | 1.0690 |
| MCF7 | HG-6-64-01 | 3.33 | uM | LJP6 | 1 | M02 | 72 | hr | 1209 | 2543 | 3823 | 0.6652 | 0.5645 |
| MCF7 | HG-6-64-01 | 3.33 | uM | LJP6 | 2 | M02 | 72 | hr | 1209 | 3566 | 4093 | 0.8711 | 0.8490 |
| MCF7 | HG-6-64-01 | 3.33 | uM | LJP6 | 3 | M02 | 72 | hr | 1209 | 3813 | 4121 | 0.9252 | 0.9140 |
| MCF7 | HG-6-64-01 | 10 | uM | LJP6 | 1 | M01 | 72 | hr | 1209 | 142 | 3823 | 0.0371 | -0.7248 |
| MCF7 | HG-6-64-01 | 10 | uM | LJP6 | 2 | M01 | 72 | hr | 1209 | 141 | 4093 | 0.0344 | -0.7053 |
| MCF7 | HG-6-64-01 | 10 | uM | LJP6 | 3 | M01 | 72 | hr | 1209 | 227 | 4121 | 0.0551 | -0.6117 |
| MCF7 | Neratinib | 0.04 | uM | LJP5 | 1 | A18 | 72 | hr | 1209 | 3260 | 3980 | 0.8191 | 0.7807 |
| MCF7 | Neratinib | 0.04 | uM | LJP5 | 2 | A18 | 72 | hr | 1209 | 3644 | 4252 | 0.8569 | 0.8367 |
| MCF7 | Neratinib | 0.04 | uM | LJP5 | 3 | A18 | 72 | hr | 1209 | 4168 | 4376 | 0.9524 | 0.9482 |
| MCF7 | Neratinib | 0.12 | uM | LJP5 | 1 | A17 | 72 | hr | 1209 | 3012 | 3980 | 0.7568 | 0.7006 |
| MCF7 | Neratinib | 0.12 | uM | LJP5 | 2 | A17 | 72 | hr | 1209 | 3386 | 4252 | 0.7962 | 0.7638 |
| MCF7 | Neratinib | 0.12 | uM | LJP5 | 3 | A17 | 72 | hr | 1209 | 3533 | 4376 | 0.8073 | 0.7821 |
| MCF7 | Neratinib | 0.37 | uM | LJP5 | 1 | A16 | 72 | hr | 1209 | 2807 | 3980 | 0.7053 | 0.6322 |
| MCF7 | Neratinib | 0.37 | uM | LJP5 | 2 | A16 | 72 | hr | 1209 | 2675 | 4252 | 0.6290 | 0.5489 |
| MCF7 | Neratinib | 0.37 | uM | LJP5 | 3 | A16 | 72 | hr | 1209 | 2777 | 4376 | 0.6346 | 0.5652 |