LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Dactolisib
10
uM
LJP5
 3
M13
 72
hr
 1209 1172 4376 0.2678 -0.0169
MCF7 Alpelisib
0.04
uM
LJP5
 1
N06
 72
hr
 1209 3362 3980 0.8447 0.8129
MCF7 Alpelisib
0.04
uM
LJP5
 2
N06
 72
hr
 1209 3152 4252 0.7412 0.6956
MCF7 Alpelisib
0.04
uM
LJP5
 3
N06
 72
hr
 1209 3336 4376 0.7623 0.7278
MCF7 Alpelisib
0.12
uM
LJP5
 1
N05
 72
hr
 1209 2668 3980 0.6703 0.5847
MCF7 Alpelisib
0.12
uM
LJP5
 2
N05
 72
hr
 1209 2956 4252 0.6951 0.6366
MCF7 Alpelisib
0.12
uM
LJP5
 3
N05
 72
hr
 1209 2683 4376 0.6131 0.5364
MCF7 Alpelisib
0.37
uM
LJP5
 1
N04
 72
hr
 1209 2036 3980 0.5116 0.3540
MCF7 Alpelisib
0.37
uM
LJP5
 2
N04
 72
hr
 1209 2127 4252 0.5001 0.3650
MCF7 Alpelisib
0.37
uM
LJP5
 3
N04
 72
hr
 1209 2045 4376 0.4673 0.3272
MCF7 Alpelisib
1.11
uM
LJP5
 1
N03
 72
hr
 1209 1761 3980 0.4425 0.2443
MCF7 Alpelisib
1.11
uM
LJP5
 2
N03
 72
hr
 1209 1803 4252 0.4240 0.2462
MCF7 Alpelisib
1.11
uM
LJP5
 3
N03
 72
hr
 1209 1774 4376 0.4054 0.2293
MCF7 Alpelisib
3.33
uM
LJP5
 1
N02
 72
hr
 1209 1522 3980 0.3824 0.1431
MCF7 Alpelisib
3.33
uM
LJP5
 2
N02
 72
hr
 1209 1413 4252 0.3323 0.0895
MCF7 Alpelisib
3.33
uM
LJP5
 3
N02
 72
hr
 1209 1443 4376 0.3297 0.0998
MCF7 Alpelisib
10
uM
LJP5
 1
N01
 72
hr
 1209 1184 3980 0.2975 -0.0124
MCF7 Alpelisib
10
uM
LJP5
 2
N01
 72
hr
 1209 1145 4252 0.2692 -0.0298
MCF7 Alpelisib
10
uM
LJP5
 3
N01
 72
hr
 1209 1062 4376 0.2427 -0.0677
MCF7 GDC-0980
0.04
uM
LJP5
 1
K24
 72
hr
 1209 1286 3980 0.3231 0.0363
MCF7 GDC-0980
0.04
uM
LJP5
 2
K24
 72
hr
 1209 1289 4252 0.3031 0.0357
MCF7 GDC-0980
0.04
uM
LJP5
 3
K24
 72
hr
 1209 1327 4376 0.3032 0.0512
MCF7 GDC-0980
0.12
uM
LJP5
 1
K23
 72
hr
 1209 1039 3980 0.2611 -0.0847
MCF7 GDC-0980
0.12
uM
LJP5
 2
K23
 72
hr
 1209 883 4252 0.2076 -0.1593
MCF7 GDC-0980
0.12
uM
LJP5
 3
K23
 72
hr
 1209 1086 4376 0.2482 -0.0564