LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Nintedanib
0.04
uM
LJP6
 2
H06
 72
hr
 1209 4293 4093 1.0486 1.0547
MCF7 Nintedanib
0.04
uM
LJP6
 3
H06
 72
hr
 1209 4061 4121 0.9854 0.9834
MCF7 Nintedanib
0.12
uM
LJP6
 1
H05
 72
hr
 1209 3696 3823 0.9668 0.9597
MCF7 Nintedanib
0.12
uM
LJP6
 2
H05
 72
hr
 1209 4051 4093 0.9895 0.9881
MCF7 Nintedanib
0.12
uM
LJP6
 3
H05
 72
hr
 1209 4036 4121 0.9793 0.9765
MCF7 Nintedanib
0.37
uM
LJP6
 1
H04
 72
hr
 1209 3441 3823 0.9001 0.8771
MCF7 Nintedanib
0.37
uM
LJP6
 2
H04
 72
hr
 1209 3525 4093 0.8611 0.8369
MCF7 Nintedanib
0.37
uM
LJP6
 3
H04
 72
hr
 1209 3518 4121 0.8536 0.8288
MCF7 Nintedanib
1.11
uM
LJP6
 1
H03
 72
hr
 1209 2561 3823 0.6699 0.5712
MCF7 Nintedanib
1.11
uM
LJP6
 2
H03
 72
hr
 1209 3020 4093 0.7377 0.6824
MCF7 Nintedanib
1.11
uM
LJP6
 3
H03
 72
hr
 1209 2873 4121 0.6971 0.6309
MCF7 Nintedanib
3.33
uM
LJP6
 1
H02
 72
hr
 1209 2332 3823 0.6100 0.4850
MCF7 Nintedanib
3.33
uM
LJP6
 2
H02
 72
hr
 1209 2366 4093 0.5779 0.4644
MCF7 Nintedanib
3.33
uM
LJP6
 3
H02
 72
hr
 1209 2536 4121 0.6154 0.5198
MCF7 Nintedanib
10
uM
LJP6
 1
H01
 72
hr
 1209 1300 3823 0.3401 0.0444
MCF7 Nintedanib
10
uM
LJP6
 2
H01
 72
hr
 1209 1361 4093 0.3325 0.0694
MCF7 Nintedanib
10
uM
LJP6
 3
H01
 72
hr
 1209 1498 4121 0.3635 0.1286
MCF7 Foretinib
0.04
uM
LJP5
 1
H12
 72
hr
 1209 4436 3980 1.1146 1.1303
MCF7 Foretinib
0.04
uM
LJP5
 2
H12
 72
hr
 1209 3976 4252 0.9349 0.9272
MCF7 Foretinib
0.04
uM
LJP5
 3
H12
 72
hr
 1209 4559 4376 1.0418 1.0446
MCF7 Foretinib
0.12
uM
LJP5
 1
H11
 72
hr
 1209 2644 3980 0.6643 0.5764
MCF7 Foretinib
0.12
uM
LJP5
 2
H11
 72
hr
 1209 2987 4252 0.7024 0.6460
MCF7 Foretinib
0.12
uM
LJP5
 3
H11
 72
hr
 1209 2938 4376 0.6714 0.6135
MCF7 Foretinib
0.37
uM
LJP5
 1
H10
 72
hr
 1209 1416 3980 0.3558 0.0960
MCF7 Foretinib
0.37
uM
LJP5
 2
H10
 72
hr
 1209 1582 4252 0.3720 0.1595