LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Linsitinib | 3.33 | uM | LJP5 | 2 | O20 | 72 | hr | 1209 | 2006 | 4252 | 0.4717 | 0.3217 |
| MCF7 | Linsitinib | 3.33 | uM | LJP5 | 3 | O20 | 72 | hr | 1209 | 1928 | 4376 | 0.4406 | 0.2857 |
| MCF7 | Linsitinib | 10 | uM | LJP5 | 1 | O19 | 72 | hr | 1209 | 1616 | 3980 | 0.4060 | 0.1836 |
| MCF7 | Linsitinib | 10 | uM | LJP5 | 2 | O19 | 72 | hr | 1209 | 1748 | 4252 | 0.4110 | 0.2251 |
| MCF7 | Linsitinib | 10 | uM | LJP5 | 3 | O19 | 72 | hr | 1209 | 1579 | 4376 | 0.3608 | 0.1545 |
| MCF7 | Ruxolitinib | 0.04 | uM | LJP5 | 1 | O18 | 72 | hr | 1209 | 3586 | 3980 | 0.9010 | 0.8823 |
| MCF7 | Ruxolitinib | 0.04 | uM | LJP5 | 2 | O18 | 72 | hr | 1209 | 4570 | 4252 | 1.0746 | 1.0809 |
| MCF7 | Ruxolitinib | 0.04 | uM | LJP5 | 3 | O18 | 72 | hr | 1209 | 4824 | 4376 | 1.1023 | 1.1078 |
| MCF7 | Ruxolitinib | 0.12 | uM | LJP5 | 1 | O17 | 72 | hr | 1209 | 4062 | 3980 | 1.0206 | 1.0239 |
| MCF7 | Ruxolitinib | 0.12 | uM | LJP5 | 2 | O17 | 72 | hr | 1209 | 4260 | 4252 | 1.0017 | 1.0019 |
| MCF7 | Ruxolitinib | 0.12 | uM | LJP5 | 3 | O17 | 72 | hr | 1209 | 4296 | 4376 | 0.9817 | 0.9802 |
| MCF7 | Ruxolitinib | 0.37 | uM | LJP5 | 1 | O16 | 72 | hr | 1209 | 3983 | 3980 | 1.0007 | 1.0009 |
| MCF7 | Ruxolitinib | 0.37 | uM | LJP5 | 2 | O16 | 72 | hr | 1209 | 4300 | 4252 | 1.0111 | 1.0122 |
| MCF7 | Ruxolitinib | 0.37 | uM | LJP5 | 3 | O16 | 72 | hr | 1209 | 4376 | 4376 | 1.0000 | 1.0000 |
| MCF7 | Ruxolitinib | 1.11 | uM | LJP5 | 1 | O15 | 72 | hr | 1209 | 4074 | 3980 | 1.0236 | 1.0273 |
| MCF7 | Ruxolitinib | 1.11 | uM | LJP5 | 2 | O15 | 72 | hr | 1209 | 4855 | 4252 | 1.1416 | 1.1515 |
| MCF7 | Ruxolitinib | 1.11 | uM | LJP5 | 3 | O15 | 72 | hr | 1209 | 4642 | 4376 | 1.0608 | 1.0646 |
| MCF7 | Ruxolitinib | 3.33 | uM | LJP5 | 1 | O14 | 72 | hr | 1209 | 4175 | 3980 | 1.0490 | 1.0564 |
| MCF7 | Ruxolitinib | 3.33 | uM | LJP5 | 2 | O14 | 72 | hr | 1209 | 4880 | 4252 | 1.1475 | 1.1576 |
| MCF7 | Ruxolitinib | 3.33 | uM | LJP5 | 3 | O14 | 72 | hr | 1209 | 4516 | 4376 | 1.0320 | 1.0342 |
| MCF7 | Ruxolitinib | 10 | uM | LJP5 | 1 | O13 | 72 | hr | 1209 | 3154 | 3980 | 0.7925 | 0.7468 |
| MCF7 | Ruxolitinib | 10 | uM | LJP5 | 2 | O13 | 72 | hr | 1209 | 3812 | 4252 | 0.8964 | 0.8829 |
| MCF7 | Ruxolitinib | 10 | uM | LJP5 | 3 | O13 | 72 | hr | 1209 | 3422 | 4376 | 0.7820 | 0.7517 |
| MCF7 | Momelotinib | 0.04 | uM | LJP5 | 1 | P12 | 72 | hr | 1209 | 3621 | 3980 | 0.9098 | 0.8929 |
| MCF7 | Momelotinib | 0.04 | uM | LJP5 | 2 | P12 | 72 | hr | 1209 | 4000 | 4252 | 0.9406 | 0.9336 |