LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | GSK 690693 | 1.11 | uM | LJP5 | 2 | F21 | 72 | hr | 1209 | 2031 | 4252 | 0.4776 | 0.3307 |
| MCF7 | GSK 690693 | 1.11 | uM | LJP5 | 3 | F21 | 72 | hr | 1209 | 1848 | 4376 | 0.4223 | 0.2567 |
| MCF7 | GSK 690693 | 3.33 | uM | LJP5 | 1 | F20 | 72 | hr | 1209 | 1868 | 3980 | 0.4693 | 0.2878 |
| MCF7 | GSK 690693 | 3.33 | uM | LJP5 | 2 | F20 | 72 | hr | 1209 | 1811 | 4252 | 0.4258 | 0.2492 |
| MCF7 | GSK 690693 | 3.33 | uM | LJP5 | 3 | F20 | 72 | hr | 1209 | 1805 | 4376 | 0.4125 | 0.2408 |
| MCF7 | GSK 690693 | 10 | uM | LJP5 | 1 | F19 | 72 | hr | 1209 | 1669 | 3980 | 0.4193 | 0.2061 |
| MCF7 | GSK 690693 | 10 | uM | LJP5 | 2 | F19 | 72 | hr | 1209 | 1737 | 4252 | 0.4084 | 0.2208 |
| MCF7 | GSK 690693 | 10 | uM | LJP5 | 3 | F19 | 72 | hr | 1209 | 1692 | 4376 | 0.3866 | 0.1983 |
| MCF7 | SNS-032 | 0.04 | uM | LJP6 | 1 | H18 | 72 | hr | 1209 | 1185 | 3823 | 0.3100 | -0.0123 |
| MCF7 | SNS-032 | 0.04 | uM | LJP6 | 2 | H18 | 72 | hr | 1209 | 1260 | 4093 | 0.3078 | 0.0235 |
| MCF7 | SNS-032 | 0.04 | uM | LJP6 | 3 | H18 | 72 | hr | 1209 | 1155 | 4121 | 0.2803 | -0.0258 |
| MCF7 | SNS-032 | 0.12 | uM | LJP6 | 1 | H17 | 72 | hr | 1209 | 773 | 3823 | 0.2022 | -0.2364 |
| MCF7 | SNS-032 | 0.12 | uM | LJP6 | 2 | H17 | 72 | hr | 1209 | 703 | 4093 | 0.1717 | -0.2655 |
| MCF7 | SNS-032 | 0.12 | uM | LJP6 | 3 | H17 | 72 | hr | 1209 | 728 | 4121 | 0.1767 | -0.2495 |
| MCF7 | SNS-032 | 0.37 | uM | LJP6 | 1 | H16 | 72 | hr | 1209 | 679 | 3823 | 0.1776 | -0.2937 |
| MCF7 | SNS-032 | 0.37 | uM | LJP6 | 2 | H16 | 72 | hr | 1209 | 736 | 4093 | 0.1798 | -0.2461 |
| MCF7 | SNS-032 | 0.37 | uM | LJP6 | 3 | H16 | 72 | hr | 1209 | 754 | 4121 | 0.1830 | -0.2345 |
| MCF7 | SNS-032 | 1.11 | uM | LJP6 | 1 | H15 | 72 | hr | 1209 | 746 | 3823 | 0.1951 | -0.2526 |
| MCF7 | SNS-032 | 1.11 | uM | LJP6 | 2 | H15 | 72 | hr | 1209 | 685 | 4093 | 0.1673 | -0.2762 |
| MCF7 | SNS-032 | 1.11 | uM | LJP6 | 3 | H15 | 72 | hr | 1209 | 729 | 4121 | 0.1769 | -0.2490 |
| MCF7 | SNS-032 | 3.33 | uM | LJP6 | 1 | H14 | 72 | hr | 1209 | 686 | 3823 | 0.1794 | -0.2894 |
| MCF7 | SNS-032 | 3.33 | uM | LJP6 | 2 | H14 | 72 | hr | 1209 | 764 | 4093 | 0.1866 | -0.2299 |
| MCF7 | SNS-032 | 3.33 | uM | LJP6 | 3 | H14 | 72 | hr | 1209 | 657 | 4121 | 0.1594 | -0.2918 |
| MCF7 | SNS-032 | 10 | uM | LJP6 | 1 | H13 | 72 | hr | 1209 | 673 | 3823 | 0.1760 | -0.2975 |
| MCF7 | SNS-032 | 10 | uM | LJP6 | 2 | H13 | 72 | hr | 1209 | 666 | 4093 | 0.1627 | -0.2877 |