LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A TGX221
3.33
uM
LJP5
 2
H20
 72
hr
 962 11104 10507 1.0567 1.0323
MCF 10A TGX221
3.33
uM
LJP5
 3
H20
 72
hr
 962 10186 10315 0.9875 0.9927
MCF 10A TGX221
10
uM
LJP5
 1
H19
 72
hr
 962 10870 10714 1.0146 1.0083
MCF 10A TGX221
10
uM
LJP5
 2
H19
 72
hr
 962 10754 10507 1.0234 1.0135
MCF 10A TGX221
10
uM
LJP5
 3
H19
 72
hr
 962 10185 10315 0.9874 0.9926
MCF 10A GSK1059615
0.04
uM
LJP6
 1
C06
 72
hr
 962 11024 10693 1.0309 1.0176
MCF 10A GSK1059615
0.04
uM
LJP6
 2
C06
 72
hr
 962 10711 10740 0.9972 0.9984
MCF 10A GSK1059615
0.04
uM
LJP6
 3
C06
 72
hr
 962 10539 10641 0.9904 0.9944
MCF 10A GSK1059615
0.04
uM
LJP5
 1
E06
 72
hr
 962 11007 10714 1.0273 1.0156
MCF 10A GSK1059615
0.04
uM
LJP5
 2
E06
 72
hr
 962 10993 10507 1.0462 1.0263
MCF 10A GSK1059615
0.04
uM
LJP5
 3
E06
 72
hr
 962 10557 10315 1.0234 1.0136
MCF 10A GSK1059615
0.12
uM
LJP6
 1
C05
 72
hr
 962 9451 10693 0.8838 0.9301
MCF 10A GSK1059615
0.12
uM
LJP6
 2
C05
 72
hr
 962 9740 10740 0.9068 0.9446
MCF 10A GSK1059615
0.12
uM
LJP6
 3
C05
 72
hr
 962 9612 10641 0.9032 0.9422
MCF 10A GSK1059615
0.12
uM
LJP5
 1
E05
 72
hr
 962 10248 10714 0.9565 0.9746
MCF 10A GSK1059615
0.12
uM
LJP5
 2
E05
 72
hr
 962 10298 10507 0.9800 0.9883
MCF 10A GSK1059615
0.12
uM
LJP5
 3
E05
 72
hr
 962 9660 10315 0.9365 0.9620
MCF 10A GSK1059615
0.37
uM
LJP6
 1
C04
 72
hr
 962 7194 10693 0.6727 0.7844
MCF 10A GSK1059615
0.37
uM
LJP6
 2
C04
 72
hr
 962 7241 10740 0.6742 0.7858
MCF 10A GSK1059615
0.37
uM
LJP6
 3
C04
 72
hr
 962 7852 10641 0.7379 0.8321
MCF 10A GSK1059615
0.37
uM
LJP5
 1
E04
 72
hr
 962 5245 10714 0.4896 0.6286
MCF 10A GSK1059615
0.37
uM
LJP5
 2
E04
 72
hr
 962 5515 10507 0.5249 0.6590
MCF 10A GSK1059615
0.37
uM
LJP5
 3
E04
 72
hr
 962 5880 10315 0.5700 0.6971
MCF 10A GSK1059615
1.11
uM
LJP6
 1
C03
 72
hr
 962 1634 10693 0.1528 0.1647
MCF 10A GSK1059615
1.11
uM
LJP6
 2
C03
 72
hr
 962 1802 10740 0.1678 0.1975