LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T PLX-4720
1.11
uM
LJP5
 1
K03
 72
hr
 658 4012 3908 1.0265 1.0204
Hs 578T PLX-4720
1.11
uM
LJP5
 2
K03
 72
hr
 658 3834 3953 0.9697 0.9764
Hs 578T PLX-4720
1.11
uM
LJP5
 3
K03
 72
hr
 658 3853 3938 0.9783 0.9831
Hs 578T PLX-4720
3.33
uM
LJP5
 1
K02
 72
hr
 658 3576 3908 0.9149 0.9320
Hs 578T PLX-4720
3.33
uM
LJP5
 2
K02
 72
hr
 658 3894 3953 0.9849 0.9883
Hs 578T PLX-4720
3.33
uM
LJP5
 3
K02
 72
hr
 658 3602 3938 0.9146 0.9320
Hs 578T PLX-4720
10
uM
LJP5
 1
K01
 72
hr
 658 2660 3908 0.6806 0.7219
Hs 578T PLX-4720
10
uM
LJP5
 2
K01
 72
hr
 658 2953 3953 0.7469 0.7866
Hs 578T PLX-4720
10
uM
LJP5
 3
K01
 72
hr
 658 2991 3938 0.7594 0.7978
Hs 578T Lapatinib
0.04
uM
LJP6
 1
M24
 72
hr
 658 3499 3705 0.9442 0.9545
Hs 578T Lapatinib
0.04
uM
LJP6
 2
M24
 72
hr
 658 3662 3807 0.9618 0.9695
Hs 578T Lapatinib
0.04
uM
LJP6
 3
M24
 72
hr
 658 3469 3769 0.9202 0.9350
Hs 578T Lapatinib
0.12
uM
LJP6
 1
M23
 72
hr
 658 3724 3705 1.0049 1.0039
Hs 578T Lapatinib
0.12
uM
LJP6
 2
M23
 72
hr
 658 3652 3807 0.9591 0.9673
Hs 578T Lapatinib
0.12
uM
LJP6
 3
M23
 72
hr
 658 3655 3769 0.9696 0.9756
Hs 578T Lapatinib
0.37
uM
LJP6
 1
M22
 72
hr
 658 3654 3705 0.9860 0.9887
Hs 578T Lapatinib
0.37
uM
LJP6
 2
M22
 72
hr
 658 3817 3807 1.0025 1.0020
Hs 578T Lapatinib
0.37
uM
LJP6
 3
M22
 72
hr
 658 3673 3769 0.9743 0.9795
Hs 578T Lapatinib
1.11
uM
LJP6
 1
M21
 72
hr
 658 3760 3705 1.0146 1.0117
Hs 578T Lapatinib
1.11
uM
LJP6
 2
M21
 72
hr
 658 3704 3807 0.9728 0.9783
Hs 578T Lapatinib
1.11
uM
LJP6
 3
M21
 72
hr
 658 3774 3769 1.0011 1.0009
Hs 578T Lapatinib
3.33
uM
LJP6
 1
M20
 72
hr
 658 3791 3705 1.0230 1.0183
Hs 578T Lapatinib
3.33
uM
LJP6
 2
M20
 72
hr
 658 3920 3807 1.0295 1.0231
Hs 578T Lapatinib
3.33
uM
LJP6
 3
M20
 72
hr
 658 4014 3769 1.0648 1.0505
Hs 578T Lapatinib
10
uM
LJP6
 1
M19
 72
hr
 658 1636 3705 0.4415 0.4408