LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 Celastrol
0.37
uM
LJP6
 3
G10
 72
hr
 1097 3303 3696 0.8936 0.8756
BT-20 Celastrol
1.11
uM
LJP6
 1
G09
 72
hr
 1097 1111 3610 0.3077 0.0073
BT-20 Celastrol
1.11
uM
LJP6
 2
G09
 72
hr
 1097 760 3713 0.2047 -0.1884
BT-20 Celastrol
1.11
uM
LJP6
 3
G09
 72
hr
 1097 588 3696 0.1591 -0.2996
BT-20 Celastrol
3.33
uM
LJP6
 1
G08
 72
hr
 1097 514 3610 0.1424 -0.3568
BT-20 Celastrol
3.33
uM
LJP6
 2
G08
 72
hr
 1097 498 3713 0.1341 -0.3618
BT-20 Celastrol
3.33
uM
LJP6
 3
G08
 72
hr
 1097 420 3696 0.1136 -0.4219
BT-20 Celastrol
10
uM
LJP6
 1
G07
 72
hr
 1097 368 3610 0.1019 -0.4705
BT-20 Celastrol
10
uM
LJP6
 2
G07
 72
hr
 1097 330 3713 0.0889 -0.4949
BT-20 Celastrol
10
uM
LJP6
 3
G07
 72
hr
 1097 301 3696 0.0814 -0.5220
BT-20 SU11274
0.04
uM
LJP5
 1
J12
 72
hr
 1097 4265 3735 1.1418 1.1559
BT-20 SU11274
0.04
uM
LJP5
 2
J12
 72
hr
 1097 3959 3877 1.0209 1.0229
BT-20 SU11274
0.04
uM
LJP5
 3
J12
 72
hr
 1097 4270 3925 1.0878 1.0936
BT-20 SU11274
0.12
uM
LJP5
 1
J11
 72
hr
 1097 4009 3735 1.0733 1.0817
BT-20 SU11274
0.12
uM
LJP5
 2
J11
 72
hr
 1097 3794 3877 0.9784 0.9762
BT-20 SU11274
0.12
uM
LJP5
 3
J11
 72
hr
 1097 4107 3925 1.0463 1.0498
BT-20 SU11274
0.37
uM
LJP5
 1
J10
 72
hr
 1097 3940 3735 1.0548 1.0613
BT-20 SU11274
0.37
uM
LJP5
 2
J10
 72
hr
 1097 3881 3877 1.0008 1.0009
BT-20 SU11274
0.37
uM
LJP5
 3
J10
 72
hr
 1097 3919 3925 0.9984 0.9982
BT-20 SU11274
1.11
uM
LJP5
 1
J09
 72
hr
 1097 3428 3735 0.9178 0.9052
BT-20 SU11274
1.11
uM
LJP5
 2
J09
 72
hr
 1097 3460 3877 0.8923 0.8787
BT-20 SU11274
1.11
uM
LJP5
 3
J09
 72
hr
 1097 3730 3925 0.9502 0.9452
BT-20 SU11274
3.33
uM
LJP5
 1
J08
 72
hr
 1097 3414 3735 0.9140 0.9008
BT-20 SU11274
3.33
uM
LJP5
 2
J08
 72
hr
 1097 3182 3877 0.8206 0.7942
BT-20 SU11274
3.33
uM
LJP5
 3
J08
 72
hr
 1097 3225 3925 0.8216 0.7973