LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
BT-20 PLX-4720
1.11
uM
LJP5
 2
K03
 72
hr
 1097 2833 3877 0.7306 0.6834
BT-20 PLX-4720
1.11
uM
LJP5
 3
K03
 72
hr
 1097 3265 3925 0.8318 0.8094
BT-20 PLX-4720
3.33
uM
LJP5
 1
K02
 72
hr
 1097 1989 3735 0.5325 0.4001
BT-20 PLX-4720
3.33
uM
LJP5
 2
K02
 72
hr
 1097 2682 3877 0.6916 0.6335
BT-20 PLX-4720
3.33
uM
LJP5
 3
K02
 72
hr
 1097 2981 3925 0.7594 0.7220
BT-20 PLX-4720
10
uM
LJP5
 1
K01
 72
hr
 1097 1525 3735 0.4083 0.2047
BT-20 PLX-4720
10
uM
LJP5
 2
K01
 72
hr
 1097 2223 3877 0.5733 0.4735
BT-20 PLX-4720
10
uM
LJP5
 3
K01
 72
hr
 1097 2189 3925 0.5577 0.4558
BT-20 Lapatinib
0.04
uM
LJP6
 1
M24
 72
hr
 1097 3228 3610 0.8940 0.8738
BT-20 Lapatinib
0.04
uM
LJP6
 2
M24
 72
hr
 1097 2936 3713 0.7906 0.7499
BT-20 Lapatinib
0.04
uM
LJP6
 3
M24
 72
hr
 1097 2584 3696 0.6991 0.6304
BT-20 Lapatinib
0.12
uM
LJP6
 1
M23
 72
hr
 1097 3364 3610 0.9317 0.9193
BT-20 Lapatinib
0.12
uM
LJP6
 2
M23
 72
hr
 1097 3286 3713 0.8848 0.8656
BT-20 Lapatinib
0.12
uM
LJP6
 3
M23
 72
hr
 1097 3192 3696 0.8635 0.8394
BT-20 Lapatinib
0.37
uM
LJP6
 1
M22
 72
hr
 1097 3278 3610 0.9079 0.8906
BT-20 Lapatinib
0.37
uM
LJP6
 2
M22
 72
hr
 1097 3302 3713 0.8891 0.8708
BT-20 Lapatinib
0.37
uM
LJP6
 3
M22
 72
hr
 1097 3541 3696 0.9580 0.9516
BT-20 Lapatinib
1.11
uM
LJP6
 1
M21
 72
hr
 1097 3652 3610 1.0115 1.0133
BT-20 Lapatinib
1.11
uM
LJP6
 2
M21
 72
hr
 1097 3562 3713 0.9592 0.9531
BT-20 Lapatinib
1.11
uM
LJP6
 3
M21
 72
hr
 1097 3516 3696 0.9512 0.9437
BT-20 Lapatinib
3.33
uM
LJP6
 1
M20
 72
hr
 1097 3293 3610 0.9120 0.8957
BT-20 Lapatinib
3.33
uM
LJP6
 2
M20
 72
hr
 1097 3396 3713 0.9145 0.9009
BT-20 Lapatinib
3.33
uM
LJP6
 3
M20
 72
hr
 1097 3494 3696 0.9452 0.9367
BT-20 Lapatinib
10
uM
LJP6
 1
M19
 72
hr
 1097 2555 3610 0.7076 0.6354
BT-20 Lapatinib
10
uM
LJP6
 2
M19
 72
hr
 1097 2543 3713 0.6848 0.6126