LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Radicicol
3.33
uM
LJP6
 2
K08
 72
hr
 1235 1160 4277 0.2712 -0.0348
MDA-MB-231 Radicicol
3.33
uM
LJP6
 3
K08
 72
hr
 1235 994 4583 0.2169 -0.1088
MDA-MB-231 Radicicol
3.33
uM
LJP5
 1
K08
 72
hr
 1235 839 4474 0.1875 -0.1884
MDA-MB-231 Radicicol
3.33
uM
LJP5
 2
K08
 72
hr
 1235 920 4578 0.2009 -0.1447
MDA-MB-231 Radicicol
3.33
uM
LJP5
 3
K08
 72
hr
 1235 991 4929 0.2010 -0.1048
MDA-MB-231 Radicicol
10
uM
LJP6
 1
K07
 72
hr
 1235 769 4355 0.1765 -0.2298
MDA-MB-231 Radicicol
10
uM
LJP6
 2
K07
 72
hr
 1235 771 4277 0.1803 -0.2316
MDA-MB-231 Radicicol
10
uM
LJP6
 3
K07
 72
hr
 1235 959 4583 0.2092 -0.1256
MDA-MB-231 Radicicol
10
uM
LJP5
 1
K07
 72
hr
 1235 781 4474 0.1745 -0.2191
MDA-MB-231 Radicicol
10
uM
LJP5
 2
K07
 72
hr
 1235 1035 4578 0.2261 -0.0896
MDA-MB-231 Radicicol
10
uM
LJP5
 3
K07
 72
hr
 1235 1099 4929 0.2230 -0.0571
MDA-MB-231 Withaferin A
0.04
uM
LJP6
 1
G18
 72
hr
 1235 4586 4355 1.0528 1.0575
MDA-MB-231 Withaferin A
0.04
uM
LJP6
 2
G18
 72
hr
 1235 4482 4277 1.0478 1.0529
MDA-MB-231 Withaferin A
0.04
uM
LJP6
 3
G18
 72
hr
 1235 4772 4583 1.0412 1.0431
MDA-MB-231 Withaferin A
0.04
uM
LJP5
 1
G18
 72
hr
 1235 4647 4474 1.0385 1.0411
MDA-MB-231 Withaferin A
0.04
uM
LJP5
 2
G18
 72
hr
 1235 4910 4578 1.0724 1.0754
MDA-MB-231 Withaferin A
0.04
uM
LJP5
 3
G18
 72
hr
 1235 5023 4929 1.0190 1.0190
MDA-MB-231 Withaferin A
0.12
uM
LJP6
 1
G17
 72
hr
 1235 4114 4355 0.9445 0.9381
MDA-MB-231 Withaferin A
0.12
uM
LJP6
 2
G17
 72
hr
 1235 4175 4277 0.9761 0.9731
MDA-MB-231 Withaferin A
0.12
uM
LJP6
 3
G17
 72
hr
 1235 4461 4583 0.9733 0.9716
MDA-MB-231 Withaferin A
0.12
uM
LJP5
 1
G17
 72
hr
 1235 4820 4474 1.0772 1.0817
MDA-MB-231 Withaferin A
0.12
uM
LJP5
 2
G17
 72
hr
 1235 4796 4578 1.0475 1.0497
MDA-MB-231 Withaferin A
0.12
uM
LJP5
 3
G17
 72
hr
 1235 5153 4929 1.0454 1.0450
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 1
G16
 72
hr
 1235 2304 4355 0.5289 0.4087
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 2
G16
 72
hr
 1235 2415 4277 0.5646 0.4535