LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Mitoxantrone | 0.12 | uM | LJP5 | 3 | C23 | 72 | hr | 1235 | 933 | 4929 | 0.1893 | -0.1314 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP6 | 1 | C22 | 72 | hr | 1235 | 614 | 4355 | 0.1410 | -0.3195 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP6 | 2 | C22 | 72 | hr | 1235 | 652 | 4277 | 0.1524 | -0.3003 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP6 | 3 | C22 | 72 | hr | 1235 | 810 | 4583 | 0.1767 | -0.2003 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP5 | 1 | C22 | 72 | hr | 1235 | 714 | 4474 | 0.1596 | -0.2559 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP5 | 2 | C22 | 72 | hr | 1235 | 795 | 4578 | 0.1736 | -0.2083 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP5 | 3 | C22 | 72 | hr | 1235 | 761 | 4929 | 0.1544 | -0.2157 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP6 | 1 | C21 | 72 | hr | 1235 | 466 | 4355 | 0.1070 | -0.4153 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP6 | 2 | C21 | 72 | hr | 1235 | 487 | 4277 | 0.1139 | -0.4055 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP6 | 3 | C21 | 72 | hr | 1235 | 415 | 4583 | 0.0905 | -0.4385 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP5 | 1 | C21 | 72 | hr | 1235 | 416 | 4474 | 0.0930 | -0.4438 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP5 | 2 | C21 | 72 | hr | 1235 | 425 | 4578 | 0.0928 | -0.4317 |
| MDA-MB-231 | Mitoxantrone | 1.11 | uM | LJP5 | 3 | C21 | 72 | hr | 1235 | 513 | 4929 | 0.1041 | -0.3564 |
| MDA-MB-231 | Mitoxantrone | 3.33 | uM | LJP6 | 1 | C20 | 72 | hr | 1235 | 197 | 4355 | 0.0452 | -0.6360 |
| MDA-MB-231 | Mitoxantrone | 3.33 | uM | LJP6 | 2 | C20 | 72 | hr | 1235 | 215 | 4277 | 0.0503 | -0.6234 |
| MDA-MB-231 | Mitoxantrone | 3.33 | uM | LJP6 | 3 | C20 | 72 | hr | 1235 | 204 | 4583 | 0.0445 | -0.6143 |
| MDA-MB-231 | Mitoxantrone | 3.33 | uM | LJP5 | 1 | C20 | 72 | hr | 1235 | 183 | 4474 | 0.0409 | -0.6427 |
| MDA-MB-231 | Mitoxantrone | 3.33 | uM | LJP5 | 2 | C20 | 72 | hr | 1235 | 185 | 4578 | 0.0404 | -0.6341 |
| MDA-MB-231 | Mitoxantrone | 3.33 | uM | LJP5 | 3 | C20 | 72 | hr | 1235 | 189 | 4929 | 0.0383 | -0.6097 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 1 | C19 | 72 | hr | 1235 | 102 | 4355 | 0.0234 | -0.7466 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 2 | C19 | 72 | hr | 1235 | 120 | 4277 | 0.0281 | -0.7280 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 1235 | 104 | 4583 | 0.0227 | -0.7299 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP5 | 1 | C19 | 72 | hr | 1235 | 96 | 4474 | 0.0215 | -0.7476 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 1235 | 75 | 4578 | 0.0164 | -0.7731 |
| MDA-MB-231 | Mitoxantrone | 10 | uM | LJP5 | 3 | C19 | 72 | hr | 1235 | 88 | 4929 | 0.0179 | -0.7339 |