LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
SK-BR-3 Withaferin A
0.37
uM
LJP5
1
G16
72
hr
1401 1864 3978 0.4685 0.2086
SK-BR-3 Withaferin A
0.37
uM
LJP5
2
G16
72
hr
1401 2298 4213 0.5454 0.3653
SK-BR-3 Withaferin A
0.37
uM
LJP5
3
G16
72
hr
1401 2310 4545 0.5082 0.3423
SK-BR-3 Withaferin A
1.11
uM
LJP6
1
G15
72
hr
1401 1325 4139 0.3201 -0.0353
SK-BR-3 Withaferin A
1.11
uM
LJP6
2
G15
72
hr
1401 1327 4095 0.3240 -0.0347
SK-BR-3 Withaferin A
1.11
uM
LJP6
3
G15
72
hr
1401 1223 4272 0.2863 -0.0812
SK-BR-3 Withaferin A
1.11
uM
LJP5
1
G15
72
hr
1401 1512 3978 0.3800 0.0517
SK-BR-3 Withaferin A
1.11
uM
LJP5
2
G15
72
hr
1401 1589 4213 0.3771 0.0823
SK-BR-3 Withaferin A
1.11
uM
LJP5
3
G15
72
hr
1401 1476 4545 0.3247 0.0310
SK-BR-3 Withaferin A
3.33
uM
LJP6
1
G14
72
hr
1401 1100 4139 0.2658 -0.1436
SK-BR-3 Withaferin A
3.33
uM
LJP6
2
G14
72
hr
1401 871 4095 0.2127 -0.2647
SK-BR-3 Withaferin A
3.33
uM
LJP6
3
G14
72
hr
1401 986 4272 0.2308 -0.1964
SK-BR-3 Withaferin A
3.33
uM
LJP5
1
G14
72
hr
1401 902 3978 0.2267 -0.2538
SK-BR-3 Withaferin A
3.33
uM
LJP5
2
G14
72
hr
1401 972 4213 0.2307 -0.2058
SK-BR-3 Withaferin A
3.33
uM
LJP5
3
G14
72
hr
1401 921 4545 0.2026 -0.2191
SK-BR-3 Withaferin A
10
uM
LJP6
1
G13
72
hr
1401 1261 4139 0.3047 -0.0654
SK-BR-3 Withaferin A
10
uM
LJP6
2
G13
72
hr
1401 1021 4095 0.2493 -0.1852
SK-BR-3 Withaferin A
10
uM
LJP6
3
G13
72
hr
1401 1178 4272 0.2757 -0.1024
SK-BR-3 Withaferin A
10
uM
LJP5
1
G13
72
hr
1401 1080 3978 0.2715 -0.1590
SK-BR-3 Withaferin A
10
uM
LJP5
2
G13
72
hr
1401 1006 4213 0.2388 -0.1885
SK-BR-3 Withaferin A
10
uM
LJP5
3
G13
72
hr
1401 968 4545 0.2129 -0.1959
SK-BR-3
uM
LJP6
1
A03
72
hr
1401 3375 4139 0.8154 0.7551
SK-BR-3
uM
LJP6
1
A04
72
hr
1401 3394 4139 0.8200 0.7614
SK-BR-3
uM
LJP6
1
A05
72
hr
1401 3832 4139 0.9258 0.9037
SK-BR-3
uM
LJP6
1
A06
72
hr
1401 3458 4139 0.8355 0.7826