LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
SK-BR-3 Radicicol
3.33
uM
LJP6
3
K08
72
hr
1401 1322 4272 0.3094 -0.0357
SK-BR-3 Radicicol
3.33
uM
LJP5
1
K08
72
hr
1401 2229 3978 0.5603 0.3610
SK-BR-3 Radicicol
3.33
uM
LJP5
2
K08
72
hr
1401 1336 4213 0.3171 -0.0297
SK-BR-3 Radicicol
3.33
uM
LJP5
3
K08
72
hr
1401 1244 4545 0.2737 -0.0678
SK-BR-3 Radicicol
10
uM
LJP6
1
K07
72
hr
1401 927 4139 0.2240 -0.2325
SK-BR-3 Radicicol
10
uM
LJP6
2
K07
72
hr
1401 987 4095 0.2410 -0.2028
SK-BR-3 Radicicol
10
uM
LJP6
3
K07
72
hr
1401 854 4272 0.1999 -0.2651
SK-BR-3 Radicicol
10
uM
LJP5
1
K07
72
hr
1401 1132 3978 0.2845 -0.1323
SK-BR-3 Radicicol
10
uM
LJP5
2
K07
72
hr
1401 990 4213 0.2350 -0.1966
SK-BR-3 Radicicol
10
uM
LJP5
3
K07
72
hr
1401 1161 4545 0.2554 -0.1050
SK-BR-3 Withaferin A
0.04
uM
LJP6
1
G18
72
hr
1401 4258 4139 1.0288 1.0366
SK-BR-3 Withaferin A
0.04
uM
LJP6
2
G18
72
hr
1401 4611 4095 1.1259 1.1593
SK-BR-3 Withaferin A
0.04
uM
LJP6
3
G18
72
hr
1401 4550 4272 1.0650 1.0799
SK-BR-3 Withaferin A
0.04
uM
LJP5
1
G18
72
hr
1401 3924 3978 0.9863 0.9817
SK-BR-3 Withaferin A
0.04
uM
LJP5
2
G18
72
hr
1401 4109 4213 0.9753 0.9687
SK-BR-3 Withaferin A
0.04
uM
LJP5
3
G18
72
hr
1401 4479 4545 0.9853 0.9826
SK-BR-3 Withaferin A
0.12
uM
LJP6
1
G17
72
hr
1401 3621 4139 0.8749 0.8360
SK-BR-3 Withaferin A
0.12
uM
LJP6
2
G17
72
hr
1401 3798 4095 0.9274 0.9049
SK-BR-3 Withaferin A
0.12
uM
LJP6
3
G17
72
hr
1401 3746 4272 0.8768 0.8430
SK-BR-3 Withaferin A
0.12
uM
LJP5
1
G17
72
hr
1401 4183 3978 1.0514 1.0677
SK-BR-3 Withaferin A
0.12
uM
LJP5
2
G17
72
hr
1401 4574 4213 1.0856 1.1062
SK-BR-3 Withaferin A
0.12
uM
LJP5
3
G17
72
hr
1401 4792 4545 1.0541 1.0631
SK-BR-3 Withaferin A
0.37
uM
LJP6
1
G16
72
hr
1401 2106 4139 0.5088 0.2978
SK-BR-3 Withaferin A
0.37
uM
LJP6
2
G16
72
hr
1401 1931 4095 0.4715 0.2302
SK-BR-3 Withaferin A
0.37
uM
LJP6
3
G16
72
hr
1401 1907 4272 0.4464 0.2111