LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PLX-4720 | 3.33 | uM | LJP5 | 1 | K02 | 72 | hr | 1401 | 2115 | 3978 | 0.5316 | 0.3144 |
| SK-BR-3 | PLX-4720 | 3.33 | uM | LJP5 | 2 | K02 | 72 | hr | 1401 | 3471 | 4213 | 0.8238 | 0.7702 |
| SK-BR-3 | PLX-4720 | 3.33 | uM | LJP5 | 3 | K02 | 72 | hr | 1401 | 4843 | 4545 | 1.0653 | 1.0760 |
| SK-BR-3 | PLX-4720 | 10 | uM | LJP5 | 1 | K01 | 72 | hr | 1401 | 1815 | 3978 | 0.4562 | 0.1874 |
| SK-BR-3 | PLX-4720 | 10 | uM | LJP5 | 2 | K01 | 72 | hr | 1401 | 2910 | 4213 | 0.6907 | 0.5842 |
| SK-BR-3 | PLX-4720 | 10 | uM | LJP5 | 3 | K01 | 72 | hr | 1401 | 3666 | 4545 | 0.8064 | 0.7620 |
| SK-BR-3 | Lapatinib | 0.04 | uM | LJP6 | 1 | M24 | 72 | hr | 1401 | 1522 | 4139 | 0.3677 | 0.0542 |
| SK-BR-3 | Lapatinib | 0.04 | uM | LJP6 | 2 | M24 | 72 | hr | 1401 | 1679 | 4095 | 0.4100 | 0.1239 |
| SK-BR-3 | Lapatinib | 0.04 | uM | LJP6 | 3 | M24 | 72 | hr | 1401 | 1757 | 4272 | 0.4113 | 0.1509 |
| SK-BR-3 | Lapatinib | 0.12 | uM | LJP6 | 1 | M23 | 72 | hr | 1401 | 1401 | 4139 | 0.3385 | -0.0002 |
| SK-BR-3 | Lapatinib | 0.12 | uM | LJP6 | 2 | M23 | 72 | hr | 1401 | 1545 | 4095 | 0.3773 | 0.0650 |
| SK-BR-3 | Lapatinib | 0.12 | uM | LJP6 | 3 | M23 | 72 | hr | 1401 | 1553 | 4272 | 0.3635 | 0.0659 |
| SK-BR-3 | Lapatinib | 0.37 | uM | LJP6 | 1 | M22 | 72 | hr | 1401 | 1432 | 4139 | 0.3460 | 0.0139 |
| SK-BR-3 | Lapatinib | 0.37 | uM | LJP6 | 2 | M22 | 72 | hr | 1401 | 1701 | 4095 | 0.4154 | 0.1334 |
| SK-BR-3 | Lapatinib | 0.37 | uM | LJP6 | 3 | M22 | 72 | hr | 1401 | 1533 | 4272 | 0.3588 | 0.0573 |
| SK-BR-3 | Lapatinib | 1.11 | uM | LJP6 | 1 | M21 | 72 | hr | 1401 | 1483 | 4139 | 0.3583 | 0.0368 |
| SK-BR-3 | Lapatinib | 1.11 | uM | LJP6 | 2 | M21 | 72 | hr | 1401 | 1714 | 4095 | 0.4185 | 0.1390 |
| SK-BR-3 | Lapatinib | 1.11 | uM | LJP6 | 3 | M21 | 72 | hr | 1401 | 1526 | 4272 | 0.3572 | 0.0543 |
| SK-BR-3 | Lapatinib | 3.33 | uM | LJP6 | 1 | M20 | 72 | hr | 1401 | 1560 | 4139 | 0.3769 | 0.0710 |
| SK-BR-3 | Lapatinib | 3.33 | uM | LJP6 | 2 | M20 | 72 | hr | 1401 | 1765 | 4095 | 0.4310 | 0.1607 |
| SK-BR-3 | Lapatinib | 3.33 | uM | LJP6 | 3 | M20 | 72 | hr | 1401 | 1682 | 4272 | 0.3937 | 0.1201 |
| SK-BR-3 | Lapatinib | 10 | uM | LJP6 | 1 | M19 | 72 | hr | 1401 | 1466 | 4139 | 0.3542 | 0.0292 |
| SK-BR-3 | Lapatinib | 10 | uM | LJP6 | 2 | M19 | 72 | hr | 1401 | 1987 | 4095 | 0.4852 | 0.2531 |
| SK-BR-3 | Lapatinib | 10 | uM | LJP6 | 3 | M19 | 72 | hr | 1401 | 1937 | 4272 | 0.4534 | 0.2229 |
| SK-BR-3 | Sirolimus | 0.04 | uM | LJP6 | 1 | L18 | 72 | hr | 1401 | 2703 | 4139 | 0.6531 | 0.5226 |