LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Neratinib
0.37
uM
LJP5
 1
A16
 72
hr
 1235 3546 4474 0.7925 0.7644
MDA-MB-231 Neratinib
0.37
uM
LJP5
 2
A16
 72
hr
 1235 3398 4578 0.7422 0.7080
MDA-MB-231 Neratinib
0.37
uM
LJP5
 3
A16
 72
hr
 1235 3669 4929 0.7443 0.7250
MDA-MB-231 Neratinib
1.11
uM
LJP5
 1
A15
 72
hr
 1235 2014 4474 0.4501 0.3009
MDA-MB-231 Neratinib
1.11
uM
LJP5
 2
A15
 72
hr
 1235 2553 4578 0.5576 0.4681
MDA-MB-231 Neratinib
1.11
uM
LJP5
 3
A15
 72
hr
 1235 2698 4929 0.5473 0.4787
MDA-MB-231 Neratinib
3.33
uM
LJP5
 1
A14
 72
hr
 1235 1507 4474 0.3368 0.1127
MDA-MB-231 Neratinib
3.33
uM
LJP5
 2
A14
 72
hr
 1235 1589 4578 0.3471 0.1422
MDA-MB-231 Neratinib
3.33
uM
LJP5
 3
A14
 72
hr
 1235 1523 4929 0.3090 0.1103
MDA-MB-231 Neratinib
10
uM
LJP5
 1
A13
 72
hr
 1235 1079 4474 0.2411 -0.0706
MDA-MB-231 Neratinib
10
uM
LJP5
 2
A13
 72
hr
 1235 801 4578 0.1750 -0.2051
MDA-MB-231 Neratinib
10
uM
LJP5
 3
A13
 72
hr
 1235 513 4929 0.1041 -0.3564
BT-20 Neratinib
0.04
uM
LJP5
 1
A18
 72
hr
 1097 2621 3735 0.7017 0.6367
BT-20 Neratinib
0.04
uM
LJP5
 2
A18
 72
hr
 1097 2956 3877 0.7623 0.7231
BT-20 Neratinib
0.04
uM
LJP5
 3
A18
 72
hr
 1097 3103 3925 0.7905 0.7600
BT-20 Neratinib
0.12
uM
LJP5
 1
A17
 72
hr
 1097 2410 3735 0.6452 0.5608
BT-20 Neratinib
0.12
uM
LJP5
 2
A17
 72
hr
 1097 2721 3877 0.7017 0.6465
BT-20 Neratinib
0.12
uM
LJP5
 3
A17
 72
hr
 1097 2749 3925 0.7003 0.6478
BT-20 Neratinib
0.37
uM
LJP5
 1
A16
 72
hr
 1097 2129 3735 0.5700 0.4551
BT-20 Neratinib
0.37
uM
LJP5
 2
A16
 72
hr
 1097 2131 3877 0.5495 0.4397
BT-20 Neratinib
0.37
uM
LJP5
 3
A16
 72
hr
 1097 2522 3925 0.6425 0.5723
BT-20 Neratinib
1.11
uM
LJP5
 1
A15
 72
hr
 1097 1890 3735 0.5060 0.3603
BT-20 Neratinib
1.11
uM
LJP5
 2
A15
 72
hr
 1097 2021 3877 0.5212 0.3984
BT-20 Neratinib
1.11
uM
LJP5
 3
A15
 72
hr
 1097 2127 3925 0.5419 0.4332
BT-20 Neratinib
3.33
uM
LJP5
 1
A14
 72
hr
 1097 1496 3735 0.4005 0.1917