LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 PLX-4720
3.33
uM
LJP5
 2
K02
 72
hr
 1209 4113 4252 0.9671 0.9635
MCF7 PLX-4720
3.33
uM
LJP5
 3
K02
 72
hr
 1209 3987 4376 0.9111 0.9021
MCF7 PLX-4720
10
uM
LJP5
 1
K01
 72
hr
 1209 2595 3980 0.6520 0.5593
MCF7 PLX-4720
10
uM
LJP5
 2
K01
 72
hr
 1209 3114 4252 0.7322 0.6843
MCF7 PLX-4720
10
uM
LJP5
 3
K01
 72
hr
 1209 3507 4376 0.8014 0.7750
MCF7 Lapatinib
0.04
uM
LJP6
 1
M24
 72
hr
 1209 3411 3823 0.8922 0.8672
MCF7 Lapatinib
0.04
uM
LJP6
 2
M24
 72
hr
 1209 3445 4093 0.8415 0.8131
MCF7 Lapatinib
0.04
uM
LJP6
 3
M24
 72
hr
 1209 3693 4121 0.8961 0.8797
MCF7 Lapatinib
0.12
uM
LJP6
 1
M23
 72
hr
 1209 3473 3823 0.9085 0.8876
MCF7 Lapatinib
0.12
uM
LJP6
 2
M23
 72
hr
 1209 3361 4093 0.8210 0.7878
MCF7 Lapatinib
0.12
uM
LJP6
 3
M23
 72
hr
 1209 3548 4121 0.8609 0.8376
MCF7 Lapatinib
0.37
uM
LJP6
 1
M22
 72
hr
 1209 3477 3823 0.9095 0.8889
MCF7 Lapatinib
0.37
uM
LJP6
 2
M22
 72
hr
 1209 3705 4093 0.9050 0.8897
MCF7 Lapatinib
0.37
uM
LJP6
 3
M22
 72
hr
 1209 3998 4121 0.9701 0.9660
MCF7 Lapatinib
1.11
uM
LJP6
 1
M21
 72
hr
 1209 3346 3823 0.8752 0.8457
MCF7 Lapatinib
1.11
uM
LJP6
 2
M21
 72
hr
 1209 3588 4093 0.8764 0.8555
MCF7 Lapatinib
1.11
uM
LJP6
 3
M21
 72
hr
 1209 3596 4121 0.8726 0.8516
MCF7 Lapatinib
3.33
uM
LJP6
 1
M20
 72
hr
 1209 3426 3823 0.8962 0.8722
MCF7 Lapatinib
3.33
uM
LJP6
 2
M20
 72
hr
 1209 3777 4093 0.9226 0.9105
MCF7 Lapatinib
3.33
uM
LJP6
 3
M20
 72
hr
 1209 3529 4121 0.8563 0.8320
MCF7 Lapatinib
10
uM
LJP6
 1
M19
 72
hr
 1209 1280 3823 0.3348 0.0347
MCF7 Lapatinib
10
uM
LJP6
 2
M19
 72
hr
 1209 1596 4093 0.3899 0.1707
MCF7 Lapatinib
10
uM
LJP6
 3
M19
 72
hr
 1209 1878 4121 0.4557 0.2824
MCF7 Sirolimus
0.04
uM
LJP6
 1
L18
 72
hr
 1209 2021 3823 0.5286 0.3623
MCF7 Sirolimus
0.04
uM
LJP6
 2
L18
 72
hr
 1209 2245 4093 0.5484 0.4213