LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | CP724714 | 3.33 | uM | LJP5 | 2 | A08 | 72 | hr | 1209 | 3783 | 4252 | 0.8895 | 0.8750 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 2 | A14 | 72 | hr | 1209 | 742 | 4093 | 0.1813 | -0.2426 |
| MCF7 | Sorafenib | 3.33 | uM | LJP6 | 3 | B08 | 72 | hr | 1209 | 3716 | 4121 | 0.9017 | 0.8863 |
| MCF7 | CP724714 | 3.33 | uM | LJP5 | 1 | A08 | 72 | hr | 1209 | 3752 | 3980 | 0.9427 | 0.9325 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 1 | A14 | 72 | hr | 1209 | 688 | 3823 | 0.1800 | -0.2881 |
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 2 | L02 | 72 | hr | 1209 | 1021 | 4093 | 0.2494 | -0.0919 |
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 1 | A08 | 72 | hr | 1209 | 957 | 3823 | 0.2503 | -0.1316 |
| MCF7 | Sorafenib | 3.33 | uM | LJP6 | 2 | B08 | 72 | hr | 1209 | 3980 | 4093 | 0.9722 | 0.9682 |
| MCF7 | CP466722 | 3.33 | uM | LJP5 | 2 | I08 | 72 | hr | 1209 | 3322 | 4252 | 0.7811 | 0.7454 |
| MCF7 | CP466722 | 3.33 | uM | LJP5 | 3 | I08 | 72 | hr | 1209 | 3050 | 4376 | 0.6970 | 0.6463 |
| MCF7 | CP724714 | 3.33 | uM | LJP5 | 3 | A08 | 72 | hr | 1209 | 3753 | 4376 | 0.8576 | 0.8411 |
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 2 | A08 | 72 | hr | 1209 | 1002 | 4093 | 0.2448 | -0.1015 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 2 | J02 | 72 | hr | 1209 | 3003 | 4252 | 0.7061 | 0.6509 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 3 | J02 | 72 | hr | 1209 | 3083 | 4376 | 0.7045 | 0.6559 |
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 3 | L02 | 72 | hr | 1209 | 992 | 4121 | 0.2407 | -0.1061 |
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 3 | A08 | 72 | hr | 1209 | 997 | 4121 | 0.2419 | -0.1035 |
| MCF7 | Sorafenib | 3.33 | uM | LJP6 | 1 | B08 | 72 | hr | 1209 | 3835 | 3823 | 1.0031 | 1.0038 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 1 | J02 | 72 | hr | 1209 | 2963 | 3980 | 0.7445 | 0.6844 |
| MCF7 | AT-7519 | 3.33 | uM | LJP6 | 3 | K02 | 72 | hr | 1209 | 500 | 4121 | 0.1213 | -0.3932 |
| MCF7 | CP466722 | 3.33 | uM | LJP5 | 1 | I08 | 72 | hr | 1209 | 3625 | 3980 | 0.9108 | 0.8941 |
| MCF7 | AT-7519 | 3.33 | uM | LJP6 | 2 | K02 | 72 | hr | 1209 | 558 | 4093 | 0.1363 | -0.3559 |
| MCF7 | AT-7519 | 3.33 | uM | LJP6 | 1 | K02 | 72 | hr | 1209 | 450 | 3823 | 0.1177 | -0.4488 |
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 1 | L02 | 72 | hr | 1209 | 967 | 3823 | 0.2529 | -0.1261 |
| MCF7 | GW843682X | 3.33 | uM | LJP6 | 1 | B14 | 72 | hr | 1209 | 1342 | 3823 | 0.3510 | 0.0646 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 3 | A14 | 72 | hr | 1209 | 652 | 4121 | 0.1582 | -0.2949 |