LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 AZD 5438
10
uM
LJP6
 1
J01
 72
hr
 1209 630 3823 0.1648 -0.3249
MCF7 AZD 5438
10
uM
LJP6
 2
J01
 72
hr
 1209 746 4093 0.1822 -0.2402
MCF7 AZD 5438
10
uM
LJP6
 3
J01
 72
hr
 1209 716 4121 0.1737 -0.2566
MCF7 Pelitinib
0.04
uM
LJP5
 1
I18
 72
hr
 1209 4286 3980 1.0769 1.0881
MCF7 Pelitinib
0.04
uM
LJP5
 2
I18
 72
hr
 1209 4159 4252 0.9780 0.9756
MCF7 Pelitinib
0.04
uM
LJP5
 3
I18
 72
hr
 1209 4752 4376 1.0859 1.0908
MCF7 Pelitinib
0.12
uM
LJP5
 1
I17
 72
hr
 1209 3798 3980 0.9543 0.9462
MCF7 Pelitinib
0.12
uM
LJP5
 2
I17
 72
hr
 1209 4374 4252 1.0285 1.0312
MCF7 Pelitinib
0.12
uM
LJP5
 3
I17
 72
hr
 1209 4375 4376 0.9997 0.9997
MCF7 Pelitinib
0.37
uM
LJP5
 1
I16
 72
hr
 1209 3804 3980 0.9558 0.9480
MCF7 Pelitinib
0.37
uM
LJP5
 2
I16
 72
hr
 1209 3888 4252 0.9142 0.9035
MCF7 Pelitinib
0.37
uM
LJP5
 3
I16
 72
hr
 1209 3763 4376 0.8599 0.8437
MCF7 Pelitinib
1.11
uM
LJP5
 1
I15
 72
hr
 1209 2733 3980 0.6867 0.6070
MCF7 Pelitinib
1.11
uM
LJP5
 2
I15
 72
hr
 1209 2961 4252 0.6963 0.6381
MCF7 Pelitinib
1.11
uM
LJP5
 3
I15
 72
hr
 1209 2743 4376 0.6268 0.5548
MCF7 Pelitinib
3.33
uM
LJP5
 1
I14
 72
hr
 1209 1645 3980 0.4133 0.1960
MCF7 Pelitinib
3.33
uM
LJP5
 2
I14
 72
hr
 1209 1753 4252 0.4122 0.2270
MCF7 Pelitinib
3.33
uM
LJP5
 3
I14
 72
hr
 1209 1826 4376 0.4173 0.2486
MCF7 Pelitinib
10
uM
LJP5
 1
I13
 72
hr
 1209 967 3980 0.2430 -0.1221
MCF7 Pelitinib
10
uM
LJP5
 2
I13
 72
hr
 1209 776 4252 0.1825 -0.2171
MCF7 Pelitinib
10
uM
LJP5
 3
I13
 72
hr
 1209 805 4376 0.1840 -0.1971
MCF7 Luminespib
0.04
uM
LJP5
 1
H18
 72
hr
 1209 1249 3980 0.3138 0.0189
MCF7 Luminespib
0.04
uM
LJP5
 2
H18
 72
hr
 1209 1246 4252 0.2930 0.0165
MCF7 Luminespib
0.04
uM
LJP5
 3
H18
 72
hr
 1209 1240 4376 0.2834 0.0135
MCF7 Luminespib
0.12
uM
LJP5
 1
H17
 72
hr
 1209 1223 3980 0.3073 0.0065