LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 SNS-032
10
uM
LJP6
3
H13
72
hr
1209 743 4121 0.1803 -0.2408
MCF7 Afatinib
0.04
uM
LJP6
1
G24
72
hr
1209 3704 3823 0.9689 0.9623
MCF7 Afatinib
0.04
uM
LJP6
2
G24
72
hr
1209 3656 4093 0.8931 0.8754
MCF7 Afatinib
0.04
uM
LJP6
3
G24
72
hr
1209 3636 4121 0.8823 0.8633
MCF7 Afatinib
0.12
uM
LJP6
1
G23
72
hr
1209 3862 3823 1.0102 1.0123
MCF7 Afatinib
0.12
uM
LJP6
2
G23
72
hr
1209 3664 4093 0.8950 0.8778
MCF7 Afatinib
0.12
uM
LJP6
3
G23
72
hr
1209 3473 4121 0.8427 0.8156
MCF7 Afatinib
0.37
uM
LJP6
1
G22
72
hr
1209 3701 3823 0.9681 0.9613
MCF7 Afatinib
0.37
uM
LJP6
2
G22
72
hr
1209 3637 4093 0.8884 0.8699
MCF7 Afatinib
0.37
uM
LJP6
3
G22
72
hr
1209 3831 4121 0.9296 0.9191
MCF7 Afatinib
1.11
uM
LJP6
1
G21
72
hr
1209 2475 3823 0.6474 0.5392
MCF7 Afatinib
1.11
uM
LJP6
2
G21
72
hr
1209 2978 4093 0.7274 0.6690
MCF7 Afatinib
1.11
uM
LJP6
3
G21
72
hr
1209 2998 4121 0.7275 0.6707
MCF7 Afatinib
3.33
uM
LJP6
1
G20
72
hr
1209 3245 3823 0.8488 0.8120
MCF7 Afatinib
3.33
uM
LJP6
2
G20
72
hr
1209 3069 4093 0.7497 0.6978
MCF7 Afatinib
3.33
uM
LJP6
3
G20
72
hr
1209 2946 4121 0.7148 0.6542
MCF7 Afatinib
10
uM
LJP6
1
G19
72
hr
1209 956 3823 0.2501 -0.1321
MCF7 Afatinib
10
uM
LJP6
2
G19
72
hr
1209 852 4093 0.2081 -0.1806
MCF7 Afatinib
10
uM
LJP6
3
G19
72
hr
1209 960 4121 0.2329 -0.1225
MCF7 GSK1904529A
0.04
uM
LJP6
1
H24
72
hr
1209 2387 3823 0.6244 0.5060
MCF7 GSK1904529A
0.04
uM
LJP6
2
H24
72
hr
1209 2315 4093 0.5655 0.4464
MCF7 GSK1904529A
0.04
uM
LJP6
3
H24
72
hr
1209 2437 4121 0.5913 0.4860
MCF7 GSK1904529A
0.12
uM
LJP6
1
H23
72
hr
1209 2263 3823 0.5919 0.4584
MCF7 GSK1904529A
0.12
uM
LJP6
2
H23
72
hr
1209 2082 4093 0.5086 0.3617
MCF7 GSK1904529A
0.12
uM
LJP6
3
H23
72
hr
1209 2462 4121 0.5974 0.4946