LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Buparlisib | 0.12 | uM | LJP5 | 3 | H05 | 72 | hr | 1209 | 1791 | 4376 | 0.4093 | 0.2356 |
| MCF7 | Buparlisib | 0.37 | uM | LJP5 | 1 | H04 | 72 | hr | 1209 | 1424 | 3980 | 0.3578 | 0.0996 |
| MCF7 | Buparlisib | 0.37 | uM | LJP5 | 2 | H04 | 72 | hr | 1209 | 1459 | 4252 | 0.3431 | 0.1089 |
| MCF7 | Buparlisib | 0.37 | uM | LJP5 | 3 | H04 | 72 | hr | 1209 | 1372 | 4376 | 0.3135 | 0.0703 |
| MCF7 | Buparlisib | 1.11 | uM | LJP5 | 1 | H03 | 72 | hr | 1209 | 978 | 3980 | 0.2457 | -0.1163 |
| MCF7 | Buparlisib | 1.11 | uM | LJP5 | 2 | H03 | 72 | hr | 1209 | 1009 | 4252 | 0.2373 | -0.0951 |
| MCF7 | Buparlisib | 1.11 | uM | LJP5 | 3 | H03 | 72 | hr | 1209 | 946 | 4376 | 0.2162 | -0.1241 |
| MCF7 | Buparlisib | 3.33 | uM | LJP5 | 1 | H02 | 72 | hr | 1209 | 856 | 3980 | 0.2151 | -0.1823 |
| MCF7 | Buparlisib | 3.33 | uM | LJP5 | 2 | H02 | 72 | hr | 1209 | 777 | 4252 | 0.1827 | -0.2165 |
| MCF7 | Buparlisib | 3.33 | uM | LJP5 | 3 | H02 | 72 | hr | 1209 | 882 | 4376 | 0.2016 | -0.1565 |
| MCF7 | Buparlisib | 10 | uM | LJP5 | 1 | H01 | 72 | hr | 1209 | 805 | 3980 | 0.2023 | -0.2110 |
| MCF7 | Buparlisib | 10 | uM | LJP5 | 2 | H01 | 72 | hr | 1209 | 855 | 4252 | 0.2010 | -0.1741 |
| MCF7 | Buparlisib | 10 | uM | LJP5 | 3 | H01 | 72 | hr | 1209 | 903 | 4376 | 0.2064 | -0.1458 |
| MCF7 | XL147 | 0.04 | uM | LJP5 | 1 | G12 | 72 | hr | 1209 | 4752 | 3980 | 1.1939 | 1.2173 |
| MCF7 | XL147 | 0.04 | uM | LJP5 | 2 | G12 | 72 | hr | 1209 | 4300 | 4252 | 1.0111 | 1.0122 |
| MCF7 | XL147 | 0.04 | uM | LJP5 | 3 | G12 | 72 | hr | 1209 | 4258 | 4376 | 0.9730 | 0.9707 |
| MCF7 | XL147 | 0.12 | uM | LJP5 | 1 | G11 | 72 | hr | 1209 | 4239 | 3980 | 1.0651 | 1.0747 |
| MCF7 | XL147 | 0.12 | uM | LJP5 | 2 | G11 | 72 | hr | 1209 | 4098 | 4252 | 0.9636 | 0.9595 |
| MCF7 | XL147 | 0.12 | uM | LJP5 | 3 | G11 | 72 | hr | 1209 | 4701 | 4376 | 1.0742 | 1.0787 |
| MCF7 | XL147 | 0.37 | uM | LJP5 | 1 | G10 | 72 | hr | 1209 | 4212 | 3980 | 1.0583 | 1.0670 |
| MCF7 | XL147 | 0.37 | uM | LJP5 | 2 | G10 | 72 | hr | 1209 | 4110 | 4252 | 0.9664 | 0.9627 |
| MCF7 | XL147 | 0.37 | uM | LJP5 | 3 | G10 | 72 | hr | 1209 | 4486 | 4376 | 1.0251 | 1.0269 |
| MCF7 | XL147 | 1.11 | uM | LJP5 | 1 | G09 | 72 | hr | 1209 | 4289 | 3980 | 1.0776 | 1.0889 |
| MCF7 | XL147 | 1.11 | uM | LJP5 | 2 | G09 | 72 | hr | 1209 | 4199 | 4252 | 0.9874 | 0.9860 |
| MCF7 | XL147 | 1.11 | uM | LJP5 | 3 | G09 | 72 | hr | 1209 | 4482 | 4376 | 1.0242 | 1.0259 |