LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Trametinib | 10 | uM | LJP5 | 2 | P19 | 72 | hr | 1209 | 2511 | 4252 | 0.5904 | 0.4958 |
| MCF7 | Trametinib | 10 | uM | LJP5 | 3 | P19 | 72 | hr | 1209 | 2158 | 4376 | 0.4931 | 0.3662 |
| MCF7 | Omipalisib | 0.04 | uM | LJP6 | 1 | N06 | 72 | hr | 1209 | 1036 | 3823 | 0.2710 | -0.0891 |
| MCF7 | Omipalisib | 0.04 | uM | LJP6 | 2 | N06 | 72 | hr | 1209 | 1117 | 4093 | 0.2729 | -0.0442 |
| MCF7 | Omipalisib | 0.04 | uM | LJP6 | 3 | N06 | 72 | hr | 1209 | 1162 | 4121 | 0.2820 | -0.0224 |
| MCF7 | Omipalisib | 0.12 | uM | LJP6 | 1 | N05 | 72 | hr | 1209 | 1049 | 3823 | 0.2744 | -0.0822 |
| MCF7 | Omipalisib | 0.12 | uM | LJP6 | 2 | N05 | 72 | hr | 1209 | 1043 | 4093 | 0.2548 | -0.0808 |
| MCF7 | Omipalisib | 0.12 | uM | LJP6 | 3 | N05 | 72 | hr | 1209 | 1072 | 4121 | 0.2601 | -0.0660 |
| MCF7 | Omipalisib | 0.37 | uM | LJP6 | 1 | N04 | 72 | hr | 1209 | 1037 | 3823 | 0.2713 | -0.0885 |
| MCF7 | Omipalisib | 0.37 | uM | LJP6 | 2 | N04 | 72 | hr | 1209 | 1128 | 4093 | 0.2755 | -0.0389 |
| MCF7 | Omipalisib | 0.37 | uM | LJP6 | 3 | N04 | 72 | hr | 1209 | 1151 | 4121 | 0.2793 | -0.0277 |
| MCF7 | Omipalisib | 1.11 | uM | LJP6 | 1 | N03 | 72 | hr | 1209 | 1143 | 3823 | 0.2990 | -0.0335 |
| MCF7 | Omipalisib | 1.11 | uM | LJP6 | 2 | N03 | 72 | hr | 1209 | 1050 | 4093 | 0.2565 | -0.0773 |
| MCF7 | Omipalisib | 1.11 | uM | LJP6 | 3 | N03 | 72 | hr | 1209 | 1113 | 4121 | 0.2701 | -0.0460 |
| MCF7 | Omipalisib | 3.33 | uM | LJP6 | 1 | N02 | 72 | hr | 1209 | 1043 | 3823 | 0.2728 | -0.0854 |
| MCF7 | Omipalisib | 3.33 | uM | LJP6 | 2 | N02 | 72 | hr | 1209 | 1092 | 4093 | 0.2667 | -0.0565 |
| MCF7 | Omipalisib | 3.33 | uM | LJP6 | 3 | N02 | 72 | hr | 1209 | 1085 | 4121 | 0.2633 | -0.0596 |
| MCF7 | Omipalisib | 10 | uM | LJP6 | 1 | N01 | 72 | hr | 1209 | 932 | 3823 | 0.2438 | -0.1453 |
| MCF7 | Omipalisib | 10 | uM | LJP6 | 2 | N01 | 72 | hr | 1209 | 917 | 4093 | 0.2240 | -0.1457 |
| MCF7 | Omipalisib | 10 | uM | LJP6 | 3 | N01 | 72 | hr | 1209 | 862 | 4121 | 0.2092 | -0.1743 |
| MCF7 | Buparlisib | 0.04 | uM | LJP5 | 1 | H06 | 72 | hr | 1209 | 2360 | 3980 | 0.5930 | 0.4755 |
| MCF7 | Buparlisib | 0.04 | uM | LJP5 | 2 | H06 | 72 | hr | 1209 | 2569 | 4252 | 0.6041 | 0.5148 |
| MCF7 | Buparlisib | 0.04 | uM | LJP5 | 3 | H06 | 72 | hr | 1209 | 2342 | 4376 | 0.5352 | 0.4278 |
| MCF7 | Buparlisib | 0.12 | uM | LJP5 | 1 | H05 | 72 | hr | 1209 | 1929 | 3980 | 0.4847 | 0.3121 |
| MCF7 | Buparlisib | 0.12 | uM | LJP5 | 2 | H05 | 72 | hr | 1209 | 1923 | 4252 | 0.4522 | 0.2912 |