LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A SU11274
3.33
uM
LJP5
 2
J08
 72
hr
 962 6880 10507 0.6548 0.7689
MCF 10A SU11274
3.33
uM
LJP5
 3
J08
 72
hr
 962 6697 10315 0.6492 0.7629
MCF 10A SU11274
10
uM
LJP5
 1
J07
 72
hr
 962 3652 10714 0.3409 0.4676
MCF 10A SU11274
10
uM
LJP5
 2
J07
 72
hr
 962 3496 10507 0.3327 0.4536
MCF 10A SU11274
10
uM
LJP5
 3
J07
 72
hr
 962 3439 10315 0.3334 0.4509
MCF 10A Canertinib
0.04
uM
LJP6
 1
H12
 72
hr
 962 7738 10693 0.7236 0.8222
MCF 10A Canertinib
0.04
uM
LJP6
 2
H12
 72
hr
 962 7463 10740 0.6948 0.8014
MCF 10A Canertinib
0.04
uM
LJP6
 3
H12
 72
hr
 962 8403 10641 0.7896 0.8683
MCF 10A Canertinib
0.12
uM
LJP6
 1
H11
 72
hr
 962 5679 10693 0.5311 0.6669
MCF 10A Canertinib
0.12
uM
LJP6
 2
H11
 72
hr
 962 5090 10740 0.4739 0.6138
MCF 10A Canertinib
0.12
uM
LJP6
 3
H11
 72
hr
 962 6088 10641 0.5721 0.7025
MCF 10A Canertinib
0.37
uM
LJP6
 1
H10
 72
hr
 962 3002 10693 0.2807 0.3875
MCF 10A Canertinib
0.37
uM
LJP6
 2
H10
 72
hr
 962 3839 10740 0.3574 0.4882
MCF 10A Canertinib
0.37
uM
LJP6
 3
H10
 72
hr
 962 3710 10641 0.3486 0.4759
MCF 10A Canertinib
1.11
uM
LJP6
 1
H09
 72
hr
 962 2144 10693 0.2005 0.2594
MCF 10A Canertinib
1.11
uM
LJP6
 2
H09
 72
hr
 962 2025 10740 0.1885 0.2384
MCF 10A Canertinib
1.11
uM
LJP6
 3
H09
 72
hr
 962 2409 10641 0.2264 0.3030
MCF 10A Canertinib
3.33
uM
LJP6
 1
H08
 72
hr
 962 1419 10693 0.1327 0.1183
MCF 10A Canertinib
3.33
uM
LJP6
 2
H08
 72
hr
 962 1487 10740 0.1384 0.1332
MCF 10A Canertinib
3.33
uM
LJP6
 3
H08
 72
hr
 962 1621 10641 0.1523 0.1623
MCF 10A Canertinib
10
uM
LJP6
 1
H07
 72
hr
 962 212 10693 0.0198 -0.3530
MCF 10A Canertinib
10
uM
LJP6
 2
H07
 72
hr
 962 193 10740 0.0180 -0.3697
MCF 10A Canertinib
10
uM
LJP6
 3
H07
 72
hr
 962 219 10641 0.0206 -0.3475
MCF 10A NVP-AEW541
0.04
uM
LJP5
 1
E18
 72
hr
 962 10766 10714 1.0049 1.0028
MCF 10A NVP-AEW541
0.04
uM
LJP5
 2
E18
 72
hr
 962 10556 10507 1.0046 1.0027