LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 3
G16
 72
hr
 1235 2762 4583 0.6026 0.5300
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 1
G16
 72
hr
 1235 2413 4474 0.5393 0.4340
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 2
G16
 72
hr
 1235 2678 4578 0.5849 0.5057
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 3
G16
 72
hr
 1235 3432 4929 0.6963 0.6682
MDA-MB-231 Withaferin A
1.11
uM
LJP6
 1
G15
 72
hr
 1235 860 4355 0.1974 -0.1809
MDA-MB-231 Withaferin A
1.11
uM
LJP6
 2
G15
 72
hr
 1235 1171 4277 0.2738 -0.0297
MDA-MB-231 Withaferin A
1.11
uM
LJP6
 3
G15
 72
hr
 1235 905 4583 0.1975 -0.1520
MDA-MB-231 Withaferin A
1.11
uM
LJP5
 1
G15
 72
hr
 1235 904 4474 0.2020 -0.1551
MDA-MB-231 Withaferin A
1.11
uM
LJP5
 2
G15
 72
hr
 1235 933 4578 0.2038 -0.1383
MDA-MB-231 Withaferin A
1.11
uM
LJP5
 3
G15
 72
hr
 1235 1172 4929 0.2378 -0.0263
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 1
G14
 72
hr
 1235 767 4355 0.1761 -0.2309
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 2
G14
 72
hr
 1235 1165 4277 0.2724 -0.0325
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 3
G14
 72
hr
 1235 762 4583 0.1663 -0.2257
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 1
G14
 72
hr
 1235 781 4474 0.1745 -0.2191
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 2
G14
 72
hr
 1235 914 4578 0.1996 -0.1476
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 3
G14
 72
hr
 1235 881 4929 0.1787 -0.1560
MDA-MB-231 Withaferin A
10
uM
LJP6
 1
G13
 72
hr
 1235 457 4355 0.1049 -0.4216
MDA-MB-231 Withaferin A
10
uM
LJP6
 2
G13
 72
hr
 1235 738 4277 0.1725 -0.2502
MDA-MB-231 Withaferin A
10
uM
LJP6
 3
G13
 72
hr
 1235 584 4583 0.1274 -0.3273
MDA-MB-231 Withaferin A
10
uM
LJP5
 1
G13
 72
hr
 1235 560 4474 0.1252 -0.3472
MDA-MB-231 Withaferin A
10
uM
LJP5
 2
G13
 72
hr
 1235 619 4578 0.1352 -0.3065
MDA-MB-231 Withaferin A
10
uM
LJP5
 3
G13
 72
hr
 1235 634 4929 0.1286 -0.2843
MDA-MB-231
uM
LJP6
 1
A03
 72
hr
 1235 3913 4355 0.8983 0.8854
MDA-MB-231
uM
LJP6
 1
A04
 72
hr
 1235 4298 4355 0.9867 0.9853
MDA-MB-231
uM
LJP6
 1
A05
 72
hr
 1235 4351 4355 0.9989 0.9988