LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 GDC-0980
0.12
uM
LJP5
 2
K23
 72
hr
 1235 2431 4578 0.5310 0.4305
MDA-MB-231 GDC-0980
0.12
uM
LJP5
 3
K23
 72
hr
 1235 2803 4929 0.5686 0.5073
MDA-MB-231 GDC-0980
0.37
uM
LJP5
 1
K22
 72
hr
 1235 1986 4474 0.4438 0.2911
MDA-MB-231 GDC-0980
0.37
uM
LJP5
 2
K22
 72
hr
 1235 1921 4578 0.4196 0.2629
MDA-MB-231 GDC-0980
0.37
uM
LJP5
 3
K22
 72
hr
 1235 2159 4929 0.4380 0.3225
MDA-MB-231 GDC-0980
1.11
uM
LJP5
 1
K21
 72
hr
 1235 1484 4474 0.3316 0.1036
MDA-MB-231 GDC-0980
1.11
uM
LJP5
 2
K21
 72
hr
 1235 1699 4578 0.3711 0.1834
MDA-MB-231 GDC-0980
1.11
uM
LJP5
 3
K21
 72
hr
 1235 1917 4929 0.3889 0.2460
MDA-MB-231 GDC-0980
3.33
uM
LJP5
 1
K20
 72
hr
 1235 1431 4474 0.3198 0.0821
MDA-MB-231 GDC-0980
3.33
uM
LJP5
 2
K20
 72
hr
 1235 1449 4578 0.3165 0.0878
MDA-MB-231 GDC-0980
3.33
uM
LJP5
 3
K20
 72
hr
 1235 1771 4929 0.3593 0.1975
MDA-MB-231 GDC-0980
10
uM
LJP5
 1
K19
 72
hr
 1235 1234 4474 0.2758 -0.0009
MDA-MB-231 GDC-0980
10
uM
LJP5
 2
K19
 72
hr
 1235 1140 4578 0.2490 -0.0419
MDA-MB-231 GDC-0980
10
uM
LJP5
 3
K19
 72
hr
 1235 1468 4929 0.2978 0.0900
MDA-MB-231 Mitoxantrone
0.04
uM
LJP6
 1
C24
 72
hr
 1235 922 4355 0.2117 -0.1489
MDA-MB-231 Mitoxantrone
0.04
uM
LJP6
 2
C24
 72
hr
 1235 957 4277 0.2237 -0.1331
MDA-MB-231 Mitoxantrone
0.04
uM
LJP6
 3
C24
 72
hr
 1235 1047 4583 0.2284 -0.0840
MDA-MB-231 Mitoxantrone
0.04
uM
LJP5
 1
C24
 72
hr
 1235 1092 4474 0.2440 -0.0645
MDA-MB-231 Mitoxantrone
0.04
uM
LJP5
 2
C24
 72
hr
 1235 977 4578 0.2134 -0.1170
MDA-MB-231 Mitoxantrone
0.04
uM
LJP5
 3
C24
 72
hr
 1235 1042 4929 0.2114 -0.0820
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 1
C23
 72
hr
 1235 891 4355 0.2046 -0.1648
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 2
C23
 72
hr
 1235 796 4277 0.1861 -0.2178
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 3
C23
 72
hr
 1235 1062 4583 0.2317 -0.0771
MDA-MB-231 Mitoxantrone
0.12
uM
LJP5
 1
C23
 72
hr
 1235 1005 4474 0.2246 -0.1055
MDA-MB-231 Mitoxantrone
0.12
uM
LJP5
 2
C23
 72
hr
 1235 939 4578 0.2051 -0.1354