LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
SK-BR-3
uM
LJP5
 3
N23
 72
hr
 1401 4269 4545 0.9391 0.9273
SK-BR-3
uM
LJP5
 3
N24
 72
hr
 1401 4124 4545 0.9072 0.8885
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 1
J06
 72
hr
 1235 4349 4474 0.9719 0.9695
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 2
J06
 72
hr
 1235 4488 4578 0.9802 0.9790
MDA-MB-231 Seliciclib
0.04
uM
LJP5
 3
J06
 72
hr
 1235 5141 4929 1.0430 1.0426
MDA-MB-231 Seliciclib
0.12
uM
LJP5
 1
J05
 72
hr
 1235 4019 4474 0.8982 0.8876
MDA-MB-231 Seliciclib
0.12
uM
LJP5
 2
J05
 72
hr
 1235 4403 4578 0.9617 0.9590
MDA-MB-231 Seliciclib
0.12
uM
LJP5
 3
J05
 72
hr
 1235 4751 4929 0.9638 0.9634
MDA-MB-231 Seliciclib
0.37
uM
LJP5
 1
J04
 72
hr
 1235 4119 4474 0.9205 0.9127
MDA-MB-231 Seliciclib
0.37
uM
LJP5
 2
J04
 72
hr
 1235 4324 4578 0.9444 0.9404
MDA-MB-231 Seliciclib
0.37
uM
LJP5
 3
J04
 72
hr
 1235 4664 4929 0.9462 0.9453
MDA-MB-231 Seliciclib
1.11
uM
LJP5
 1
J03
 72
hr
 1235 3745 4474 0.8369 0.8171
MDA-MB-231 Seliciclib
1.11
uM
LJP5
 2
J03
 72
hr
 1235 4032 4578 0.8806 0.8699
MDA-MB-231 Seliciclib
1.11
uM
LJP5
 3
J03
 72
hr
 1235 4573 4929 0.9277 0.9262
MDA-MB-231 Seliciclib
3.33
uM
LJP5
 1
J02
 72
hr
 1235 3463 4474 0.7739 0.7421
MDA-MB-231 Seliciclib
3.33
uM
LJP5
 2
J02
 72
hr
 1235 3698 4578 0.8077 0.7862
MDA-MB-231 Seliciclib
3.33
uM
LJP5
 3
J02
 72
hr
 1235 4103 4929 0.8324 0.8243
MDA-MB-231 Seliciclib
10
uM
LJP5
 1
J01
 72
hr
 1235 2296 4474 0.5131 0.3961
MDA-MB-231 Seliciclib
10
uM
LJP5
 2
J01
 72
hr
 1235 2364 4578 0.5163 0.4095
MDA-MB-231 Seliciclib
10
uM
LJP5
 3
J01
 72
hr
 1235 2730 4929 0.5538 0.4875
MDA-MB-231 AT-7519
0.04
uM
LJP6
 1
K06
 72
hr
 1235 2685 4355 0.6164 0.5325
MDA-MB-231 AT-7519
0.04
uM
LJP6
 2
K06
 72
hr
 1235 2631 4277 0.6151 0.5247
MDA-MB-231 AT-7519
0.04
uM
LJP6
 3
K06
 72
hr
 1235 2664 4583 0.5812 0.5011
MDA-MB-231 AT-7519
0.12
uM
LJP6
 1
K05
 72
hr
 1235 1114 4355 0.2557 -0.0556
MDA-MB-231 AT-7519
0.12
uM
LJP6
 2
K05
 72
hr
 1235 739 4277 0.1728 -0.2496