LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | CGP60474 | 10 | uM | LJP5 | 1 | F01 | 72 | hr | 1209 | 617 | 3980 | 0.1550 | -0.3241 |
| MCF7 | CGP60474 | 10 | uM | LJP5 | 2 | F01 | 72 | hr | 1209 | 537 | 4252 | 0.1263 | -0.3609 |
| MCF7 | CGP60474 | 10 | uM | LJP5 | 3 | F01 | 72 | hr | 1209 | 551 | 4376 | 0.1259 | -0.3455 |
| MCF7 | PD173074 | 0.04 | uM | LJP6 | 1 | I12 | 72 | hr | 1209 | 4110 | 3823 | 1.0751 | 1.0891 |
| MCF7 | PD173074 | 0.04 | uM | LJP6 | 2 | I12 | 72 | hr | 1209 | 4077 | 4093 | 0.9959 | 0.9953 |
| MCF7 | PD173074 | 0.04 | uM | LJP6 | 3 | I12 | 72 | hr | 1209 | 4058 | 4121 | 0.9847 | 0.9826 |
| MCF7 | PD173074 | 0.12 | uM | LJP6 | 1 | I11 | 72 | hr | 1209 | 4312 | 3823 | 1.1279 | 1.1504 |
| MCF7 | PD173074 | 0.12 | uM | LJP6 | 2 | I11 | 72 | hr | 1209 | 4209 | 4093 | 1.0281 | 1.0318 |
| MCF7 | PD173074 | 0.12 | uM | LJP6 | 3 | I11 | 72 | hr | 1209 | 3985 | 4121 | 0.9670 | 0.9624 |
| MCF7 | PD173074 | 0.37 | uM | LJP6 | 1 | I10 | 72 | hr | 1209 | 4021 | 3823 | 1.0518 | 1.0618 |
| MCF7 | PD173074 | 0.37 | uM | LJP6 | 2 | I10 | 72 | hr | 1209 | 4196 | 4093 | 1.0250 | 1.0282 |
| MCF7 | PD173074 | 0.37 | uM | LJP6 | 3 | I10 | 72 | hr | 1209 | 3545 | 4121 | 0.8602 | 0.8367 |
| MCF7 | PD173074 | 1.11 | uM | LJP6 | 1 | I09 | 72 | hr | 1209 | 4281 | 3823 | 1.1198 | 1.1411 |
| MCF7 | PD173074 | 1.11 | uM | LJP6 | 2 | I09 | 72 | hr | 1209 | 4328 | 4093 | 1.0572 | 1.0642 |
| MCF7 | PD173074 | 1.11 | uM | LJP6 | 3 | I09 | 72 | hr | 1209 | 4208 | 4121 | 1.0211 | 1.0237 |
| MCF7 | PD173074 | 3.33 | uM | LJP6 | 1 | I08 | 72 | hr | 1209 | 3914 | 3823 | 1.0238 | 1.0285 |
| MCF7 | PD173074 | 3.33 | uM | LJP6 | 2 | I08 | 72 | hr | 1209 | 3895 | 4093 | 0.9514 | 0.9442 |
| MCF7 | PD173074 | 3.33 | uM | LJP6 | 3 | I08 | 72 | hr | 1209 | 3971 | 4121 | 0.9636 | 0.9585 |
| MCF7 | PD173074 | 10 | uM | LJP6 | 1 | I07 | 72 | hr | 1209 | 2768 | 3823 | 0.7240 | 0.6465 |
| MCF7 | PD173074 | 10 | uM | LJP6 | 2 | I07 | 72 | hr | 1209 | 2527 | 4093 | 0.6173 | 0.5202 |
| MCF7 | PD173074 | 10 | uM | LJP6 | 3 | I07 | 72 | hr | 1209 | 2785 | 4121 | 0.6758 | 0.6025 |
| MCF7 | Crizotinib | 0.04 | uM | LJP5 | 1 | A24 | 72 | hr | 1209 | 3430 | 3980 | 0.8618 | 0.8342 |
| MCF7 | Crizotinib | 0.04 | uM | LJP5 | 2 | A24 | 72 | hr | 1209 | 3750 | 4252 | 0.8818 | 0.8660 |
| MCF7 | Crizotinib | 0.04 | uM | LJP5 | 3 | A24 | 72 | hr | 1209 | 3683 | 4376 | 0.8416 | 0.8225 |
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 1 | A23 | 72 | hr | 1209 | 3479 | 3980 | 0.8741 | 0.8494 |