LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HG-6-64-01 | 0.04 | uM | LJP6 | 2 | M06 | 72 | hr | 1389 | 6304 | 5447 | 1.1571 | 1.1537 |
| MCF7 | HG-6-64-01 | 0.04 | uM | LJP6 | 3 | M06 | 72 | hr | 1389 | 6226 | 5740 | 1.0846 | 1.0809 |
| MCF7 | HG-6-64-01 | 0.12 | uM | LJP6 | 1 | M05 | 72 | hr | 1389 | 5922 | 5147 | 1.1506 | 1.1541 |
| MCF7 | HG-6-64-01 | 0.12 | uM | LJP6 | 2 | M05 | 72 | hr | 1389 | 6112 | 5447 | 1.1219 | 1.1201 |
| MCF7 | HG-6-64-01 | 0.12 | uM | LJP6 | 3 | M05 | 72 | hr | 1389 | 5911 | 5740 | 1.0297 | 1.0288 |
| MCF7 | HG-6-64-01 | 0.37 | uM | LJP6 | 1 | M04 | 72 | hr | 1389 | 6022 | 5147 | 1.1700 | 1.1733 |
| MCF7 | HG-6-64-01 | 0.37 | uM | LJP6 | 2 | M04 | 72 | hr | 1389 | 5577 | 5447 | 1.0237 | 1.0239 |
| MCF7 | HG-6-64-01 | 0.37 | uM | LJP6 | 3 | M04 | 72 | hr | 1389 | 5545 | 5740 | 0.9659 | 0.9664 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 1 | M03 | 72 | hr | 1389 | 5788 | 5147 | 1.1245 | 1.1282 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 2 | M03 | 72 | hr | 1389 | 5439 | 5447 | 0.9984 | 0.9983 |
| MCF7 | HG-6-64-01 | 1.11 | uM | LJP6 | 3 | M03 | 72 | hr | 1389 | 5222 | 5740 | 0.9097 | 0.9096 |
| MCF7 | HG-6-64-01 | 3.33 | uM | LJP6 | 1 | M02 | 72 | hr | 1389 | 3126 | 5147 | 0.6073 | 0.5361 |
| MCF7 | HG-6-64-01 | 3.33 | uM | LJP6 | 2 | M02 | 72 | hr | 1389 | 3760 | 5447 | 0.6902 | 0.6571 |
| MCF7 | HG-6-64-01 | 3.33 | uM | LJP6 | 3 | M02 | 72 | hr | 1389 | 3462 | 5740 | 0.6031 | 0.5622 |
| MCF7 | HG-6-64-01 | 10 | uM | LJP6 | 1 | M01 | 72 | hr | 1389 | 908 | 5147 | 0.1764 | -0.2015 |
| MCF7 | HG-6-64-01 | 10 | uM | LJP6 | 2 | M01 | 72 | hr | 1389 | 930 | 5447 | 0.1707 | -0.1841 |
| MCF7 | HG-6-64-01 | 10 | uM | LJP6 | 3 | M01 | 72 | hr | 1389 | 850 | 5740 | 0.1481 | -0.2133 |
| MCF7 | Neratinib | 0.04 | uM | LJP5 | 1 | A18 | 72 | hr | 1389 | 3750 | 5772 | 0.6496 | 0.6213 |
| MCF7 | Neratinib | 0.04 | uM | LJP5 | 3 | A18 | 72 | hr | 1389 | 3724 | 6038 | 0.6167 | 0.5923 |
| MCF7 | Neratinib | 0.12 | uM | LJP5 | 1 | A17 | 72 | hr | 1389 | 3487 | 5772 | 0.6041 | 0.5650 |
| MCF7 | Neratinib | 0.12 | uM | LJP5 | 3 | A17 | 72 | hr | 1389 | 4494 | 6038 | 0.7442 | 0.7399 |
| MCF7 | Neratinib | 0.37 | uM | LJP5 | 1 | A16 | 72 | hr | 1389 | 3643 | 5772 | 0.6311 | 0.5987 |
| MCF7 | Neratinib | 0.37 | uM | LJP5 | 3 | A16 | 72 | hr | 1389 | 4061 | 6038 | 0.6725 | 0.6587 |
| MCF7 | Neratinib | 1.11 | uM | LJP5 | 1 | A15 | 72 | hr | 1389 | 3438 | 5772 | 0.5956 | 0.5542 |
| MCF7 | Neratinib | 1.11 | uM | LJP5 | 3 | A15 | 72 | hr | 1389 | 4286 | 6038 | 0.7098 | 0.7014 |