LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | GSK1059615 | 1.11 | uM | LJP5 | 3 | E03 | 72 | hr | 1389 | 2793 | 6038 | 0.4625 | 0.3902 |
| MCF7 | GSK1059615 | 3.33 | uM | LJP6 | 1 | C02 | 72 | hr | 1389 | 1592 | 5147 | 0.3093 | 0.0748 |
| MCF7 | GSK1059615 | 3.33 | uM | LJP6 | 2 | C02 | 72 | hr | 1389 | 1747 | 5447 | 0.3207 | 0.1233 |
| MCF7 | GSK1059615 | 3.33 | uM | LJP6 | 3 | C02 | 72 | hr | 1389 | 1794 | 5740 | 0.3125 | 0.1331 |
| MCF7 | GSK1059615 | 3.33 | uM | LJP5 | 1 | E02 | 72 | hr | 1389 | 1378 | 5772 | 0.2387 | -0.0039 |
| MCF7 | GSK1059615 | 3.33 | uM | LJP5 | 3 | E02 | 72 | hr | 1389 | 1368 | 6038 | 0.2266 | -0.0072 |
| MCF7 | GSK1059615 | 10 | uM | LJP6 | 1 | C01 | 72 | hr | 1389 | 973 | 5147 | 0.1890 | -0.1717 |
| MCF7 | GSK1059615 | 10 | uM | LJP6 | 2 | C01 | 72 | hr | 1389 | 1035 | 5447 | 0.1900 | -0.1386 |
| MCF7 | GSK1059615 | 10 | uM | LJP6 | 3 | C01 | 72 | hr | 1389 | 1173 | 5740 | 0.2043 | -0.0793 |
| MCF7 | GSK1059615 | 10 | uM | LJP5 | 1 | E01 | 72 | hr | 1389 | 1083 | 5772 | 0.1876 | -0.1141 |
| MCF7 | GSK1059615 | 10 | uM | LJP5 | 3 | E01 | 72 | hr | 1389 | 1251 | 6038 | 0.2072 | -0.0482 |
| MCF7 | Brivanib | 0.04 | uM | LJP5 | 1 | P18 | 72 | hr | 1389 | 5238 | 5772 | 0.9074 | 0.9076 |
| MCF7 | Brivanib | 0.04 | uM | LJP5 | 3 | P18 | 72 | hr | 1389 | 5456 | 6038 | 0.9035 | 0.9066 |
| MCF7 | Brivanib | 0.12 | uM | LJP5 | 1 | P17 | 72 | hr | 1389 | 4738 | 5772 | 0.8208 | 0.8168 |
| MCF7 | Brivanib | 0.12 | uM | LJP5 | 3 | P17 | 72 | hr | 1389 | 5765 | 6038 | 0.9547 | 0.9568 |
| MCF7 | Brivanib | 0.37 | uM | LJP5 | 1 | P16 | 72 | hr | 1389 | 5470 | 5772 | 0.9476 | 0.9483 |
| MCF7 | Brivanib | 0.37 | uM | LJP5 | 3 | P16 | 72 | hr | 1389 | 5805 | 6038 | 0.9613 | 0.9631 |
| MCF7 | Brivanib | 1.11 | uM | LJP5 | 1 | P15 | 72 | hr | 1389 | 5491 | 5772 | 0.9512 | 0.9519 |
| MCF7 | Brivanib | 1.11 | uM | LJP5 | 3 | P15 | 72 | hr | 1389 | 5673 | 6038 | 0.9395 | 0.9420 |
| MCF7 | Brivanib | 3.33 | uM | LJP5 | 1 | P14 | 72 | hr | 1389 | 5611 | 5772 | 0.9720 | 0.9726 |
| MCF7 | Brivanib | 3.33 | uM | LJP5 | 3 | P14 | 72 | hr | 1389 | 5854 | 6038 | 0.9695 | 0.9709 |
| MCF7 | Brivanib | 10 | uM | LJP5 | 1 | P13 | 72 | hr | 1389 | 4798 | 5772 | 0.8312 | 0.8279 |
| MCF7 | Brivanib | 10 | uM | LJP5 | 3 | P13 | 72 | hr | 1389 | 5325 | 6038 | 0.8818 | 0.8848 |
| MCF7 | CHIR-99021 | 0.04 | uM | LJP6 | 1 | P18 | 72 | hr | 1389 | 2893 | 5147 | 0.5621 | 0.4744 |
| MCF7 | CHIR-99021 | 0.04 | uM | LJP6 | 2 | P18 | 72 | hr | 1389 | 5058 | 5447 | 0.9284 | 0.9261 |