LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A PI103
10
uM
LJP6
 1
I13
 72
hr
 1694 2370 11220 0.2112 0.1310
MCF 10A PI103
10
uM
LJP6
 2
I13
 72
hr
 1694 2283 11309 0.2019 0.1151
MCF 10A PI103
10
uM
LJP6
 3
I13
 72
hr
 1694 2028 11121 0.1824 0.0685
MCF 10A Dovitinib
0.04
uM
LJP5
 1
E24
 72
hr
 1694 10354 11042 0.9377 0.9530
MCF 10A Dovitinib
0.04
uM
LJP5
 2
E24
 72
hr
 1694 10245 11099 0.9230 0.9418
MCF 10A Dovitinib
0.04
uM
LJP5
 3
E24
 72
hr
 1694 10500 11168 0.9402 0.9552
MCF 10A Dovitinib
0.12
uM
LJP5
 1
E23
 72
hr
 1694 9247 11042 0.8374 0.8730
MCF 10A Dovitinib
0.12
uM
LJP5
 2
E23
 72
hr
 1694 9540 11099 0.8595 0.8914
MCF 10A Dovitinib
0.12
uM
LJP5
 3
E23
 72
hr
 1694 9954 11168 0.8913 0.9172
MCF 10A Dovitinib
0.37
uM
LJP5
 1
E22
 72
hr
 1694 7437 11042 0.6735 0.7280
MCF 10A Dovitinib
0.37
uM
LJP5
 2
E22
 72
hr
 1694 6784 11099 0.6112 0.6680
MCF 10A Dovitinib
0.37
uM
LJP5
 3
E22
 72
hr
 1694 7063 11168 0.6324 0.6900
MCF 10A Dovitinib
1.11
uM
LJP5
 1
E21
 72
hr
 1694 5232 11042 0.4738 0.5173
MCF 10A Dovitinib
1.11
uM
LJP5
 2
E21
 72
hr
 1694 5788 11099 0.5215 0.5731
MCF 10A Dovitinib
1.11
uM
LJP5
 3
E21
 72
hr
 1694 5107 11168 0.4573 0.5001
MCF 10A Dovitinib
3.33
uM
LJP5
 1
E20
 72
hr
 1694 2869 11042 0.2598 0.2150
MCF 10A Dovitinib
3.33
uM
LJP5
 2
E20
 72
hr
 1694 2789 11099 0.2513 0.2018
MCF 10A Dovitinib
3.33
uM
LJP5
 3
E20
 72
hr
 1694 2916 11168 0.2611 0.2209
MCF 10A Dovitinib
10
uM
LJP5
 1
E19
 72
hr
 1694 1897 11042 0.1718 0.0427
MCF 10A Dovitinib
10
uM
LJP5
 2
E19
 72
hr
 1694 1965 11099 0.1770 0.0562
MCF 10A Dovitinib
10
uM
LJP5
 3
E19
 72
hr
 1694 1899 11168 0.1700 0.0428
MCF 10A GSK 690693
0.04
uM
LJP5
 1
F24
 72
hr
 1694 11293 11042 1.0227 1.0167
MCF 10A GSK 690693
0.04
uM
LJP5
 2
F24
 72
hr
 1694 11084 11099 0.9986 0.9990
MCF 10A GSK 690693
0.04
uM
LJP5
 3
F24
 72
hr
 1694 11469 11168 1.0269 1.0196
MCF 10A GSK 690693
0.12
uM
LJP5
 1
F23
 72
hr
 1694 11208 11042 1.0150 1.0110