LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Celastrol
0.12
uM
LJP6
 3
G11
 72
hr
 1694 12367 11121 1.1120 1.0798
MCF 10A Celastrol
0.37
uM
LJP6
 1
G10
 72
hr
 1694 11576 11220 1.0316 1.0230
MCF 10A Celastrol
0.37
uM
LJP6
 2
G10
 72
hr
 1694 11712 11309 1.0356 1.0257
MCF 10A Celastrol
0.37
uM
LJP6
 3
G10
 72
hr
 1694 11601 11121 1.0431 1.0314
MCF 10A Celastrol
1.11
uM
LJP6
 1
G09
 72
hr
 1694 5306 11220 0.4729 0.5198
MCF 10A Celastrol
1.11
uM
LJP6
 2
G09
 72
hr
 1694 7432 11309 0.6572 0.7158
MCF 10A Celastrol
1.11
uM
LJP6
 3
G09
 72
hr
 1694 7541 11121 0.6781 0.7333
MCF 10A Celastrol
3.33
uM
LJP6
 1
G08
 72
hr
 1694 266 11220 0.0237 -0.4928
MCF 10A Celastrol
3.33
uM
LJP6
 2
G08
 72
hr
 1694 520 11309 0.0460 -0.3503
MCF 10A Celastrol
3.33
uM
LJP6
 3
G08
 72
hr
 1694 423 11121 0.0380 -0.4002
MCF 10A Celastrol
10
uM
LJP6
 1
G07
 72
hr
 1694 745 11220 0.0664 -0.2601
MCF 10A Celastrol
10
uM
LJP6
 2
G07
 72
hr
 1694 766 11309 0.0677 -0.2516
MCF 10A Celastrol
10
uM
LJP6
 3
G07
 72
hr
 1694 902 11121 0.0811 -0.2072
MCF 10A SU11274
0.04
uM
LJP5
 1
J12
 72
hr
 1694 11305 11042 1.0238 1.0175
MCF 10A SU11274
0.04
uM
LJP5
 2
J12
 72
hr
 1694 11545 11099 1.0401 1.0292
MCF 10A SU11274
0.04
uM
LJP5
 3
J12
 72
hr
 1694 11370 11168 1.0181 1.0132
MCF 10A SU11274
0.12
uM
LJP5
 1
J11
 72
hr
 1694 11001 11042 0.9963 0.9972
MCF 10A SU11274
0.12
uM
LJP5
 2
J11
 72
hr
 1694 10873 11099 0.9796 0.9849
MCF 10A SU11274
0.12
uM
LJP5
 3
J11
 72
hr
 1694 10937 11168 0.9793 0.9847
MCF 10A SU11274
0.37
uM
LJP5
 1
J10
 72
hr
 1694 10323 11042 0.9349 0.9508
MCF 10A SU11274
0.37
uM
LJP5
 2
J10
 72
hr
 1694 10284 11099 0.9265 0.9445
MCF 10A SU11274
0.37
uM
LJP5
 3
J10
 72
hr
 1694 10380 11168 0.9294 0.9469
MCF 10A SU11274
1.11
uM
LJP5
 1
J09
 72
hr
 1694 9103 11042 0.8244 0.8622
MCF 10A SU11274
1.11
uM
LJP5
 2
J09
 72
hr
 1694 8920 11099 0.8036 0.8451
MCF 10A SU11274
1.11
uM
LJP5
 3
J09
 72
hr
 1694 9288 11168 0.8316 0.8690