LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T SU11274
3.33
uM
LJP5
 2
J08
 72
hr
 765 2576 3151 0.8174 0.8120
Hs 578T SU11274
3.33
uM
LJP5
 3
J08
 72
hr
 765 2592 3152 0.8222 0.8173
Hs 578T SU11274
10
uM
LJP5
 1
J07
 72
hr
 765 847 3140 0.2697 0.0512
Hs 578T SU11274
10
uM
LJP5
 2
J07
 72
hr
 765 866 3151 0.2748 0.0626
Hs 578T SU11274
10
uM
LJP5
 3
J07
 72
hr
 765 946 3152 0.3001 0.1095
Hs 578T Canertinib
0.04
uM
LJP6
 1
H12
 72
hr
 765 3095 3143 0.9845 0.9847
Hs 578T Canertinib
0.04
uM
LJP6
 2
H12
 72
hr
 765 2959 3095 0.9559 0.9557
Hs 578T Canertinib
0.04
uM
LJP6
 3
H12
 72
hr
 765 3016 3066 0.9837 0.9837
Hs 578T Canertinib
0.12
uM
LJP6
 1
H11
 72
hr
 765 3092 3143 0.9835 0.9838
Hs 578T Canertinib
0.12
uM
LJP6
 2
H11
 72
hr
 765 3037 3095 0.9811 0.9811
Hs 578T Canertinib
0.12
uM
LJP6
 3
H11
 72
hr
 765 3000 3066 0.9785 0.9784
Hs 578T Canertinib
0.37
uM
LJP6
 1
H10
 72
hr
 765 2931 3143 0.9323 0.9324
Hs 578T Canertinib
0.37
uM
LJP6
 2
H10
 72
hr
 765 2913 3095 0.9410 0.9406
Hs 578T Canertinib
0.37
uM
LJP6
 3
H10
 72
hr
 765 3010 3066 0.9817 0.9817
Hs 578T Canertinib
1.11
uM
LJP6
 1
H09
 72
hr
 765 2953 3143 0.9393 0.9395
Hs 578T Canertinib
1.11
uM
LJP6
 2
H09
 72
hr
 765 2952 3095 0.9536 0.9534
Hs 578T Canertinib
1.11
uM
LJP6
 3
H09
 72
hr
 765 2876 3066 0.9380 0.9371
Hs 578T Canertinib
3.33
uM
LJP6
 1
H08
 72
hr
 765 2784 3143 0.8856 0.8843
Hs 578T Canertinib
3.33
uM
LJP6
 2
H08
 72
hr
 765 2743 3095 0.8861 0.8836
Hs 578T Canertinib
3.33
uM
LJP6
 3
H08
 72
hr
 765 2723 3066 0.8881 0.8850
Hs 578T Canertinib
10
uM
LJP6
 1
H07
 72
hr
 765 214 3143 0.0681 -0.4647
Hs 578T Canertinib
10
uM
LJP6
 2
H07
 72
hr
 765 262 3095 0.0846 -0.4122
Hs 578T Canertinib
10
uM
LJP6
 3
H07
 72
hr
 765 246 3066 0.0802 -0.4325
Hs 578T NVP-AEW541
0.04
uM
LJP5
 1
E18
 72
hr
 765 3184 3140 1.0139 1.0136
Hs 578T NVP-AEW541
0.04
uM
LJP5
 2
E18
 72
hr
 765 3263 3151 1.0353 1.0343