LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 MK2206
0.04
uM
LJP6
 3
F06
 72
hr
 1311 4800 4973 0.9651 0.9634
MDA-MB-231 MK2206
0.12
uM
LJP6
 1
F05
 72
hr
 1311 4679 4870 0.9607 0.9581
MDA-MB-231 MK2206
0.12
uM
LJP6
 2
F05
 72
hr
 1311 4696 4961 0.9465 0.9435
MDA-MB-231 MK2206
0.12
uM
LJP6
 3
F05
 72
hr
 1311 4670 4973 0.9389 0.9355
MDA-MB-231 MK2206
0.37
uM
LJP6
 1
F04
 72
hr
 1311 4293 4870 0.8815 0.8710
MDA-MB-231 MK2206
0.37
uM
LJP6
 2
F04
 72
hr
 1311 4143 4961 0.8350 0.8207
MDA-MB-231 MK2206
0.37
uM
LJP6
 3
F04
 72
hr
 1311 4062 4973 0.8167 0.8001
MDA-MB-231 MK2206
1.11
uM
LJP6
 1
F03
 72
hr
 1311 4116 4870 0.8451 0.8299
MDA-MB-231 MK2206
1.11
uM
LJP6
 2
F03
 72
hr
 1311 4363 4961 0.8794 0.8704
MDA-MB-231 MK2206
1.11
uM
LJP6
 3
F03
 72
hr
 1311 4405 4973 0.8856 0.8776
MDA-MB-231 MK2206
3.33
uM
LJP6
 1
F02
 72
hr
 1311 3911 4870 0.8030 0.7811
MDA-MB-231 MK2206
3.33
uM
LJP6
 2
F02
 72
hr
 1311 4227 4961 0.8519 0.8398
MDA-MB-231 MK2206
3.33
uM
LJP6
 3
F02
 72
hr
 1311 4108 4973 0.8259 0.8107
MDA-MB-231 MK2206
10
uM
LJP6
 1
F01
 72
hr
 1311 4040 4870 0.8295 0.8119
MDA-MB-231 MK2206
10
uM
LJP6
 2
F01
 72
hr
 1311 3606 4961 0.7268 0.6936
MDA-MB-231 MK2206
10
uM
LJP6
 3
F01
 72
hr
 1311 4287 4973 0.8619 0.8513
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 1
I06
 72
hr
 1311 4795 5128 0.9350 0.9328
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 2
I06
 72
hr
 1311 4671 5100 0.9159 0.9123
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 3
I06
 72
hr
 1311 4983 5010 0.9944 0.9942
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 1
I05
 72
hr
 1311 4558 5128 0.8888 0.8836
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 2
I05
 72
hr
 1311 4398 5100 0.8624 0.8544
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 3
I05
 72
hr
 1311 4712 5010 0.9404 0.9374
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 1
I04
 72
hr
 1311 4576 5128 0.8923 0.8874
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 2
I04
 72
hr
 1311 4486 5100 0.8796 0.8732
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 3
I04
 72
hr
 1311 4423 5010 0.8827 0.8750