LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PLX-4720 | 1.11 | uM | LJP5 | 3 | K03 | 72 | hr | 2543 | 6056 | 5760 | 1.0512 | 1.0865 |
| SK-BR-3 | PLX-4720 | 3.33 | uM | LJP5 | 1 | K02 | 72 | hr | 2543 | 4862 | 5734 | 0.8479 | 0.7375 |
| SK-BR-3 | PLX-4720 | 3.33 | uM | LJP5 | 2 | K02 | 72 | hr | 2543 | 2815 | 5761 | 0.4886 | 0.0898 |
| SK-BR-3 | PLX-4720 | 3.33 | uM | LJP5 | 3 | K02 | 72 | hr | 2543 | 4815 | 5760 | 0.8358 | 0.7179 |
| SK-BR-3 | PLX-4720 | 10 | uM | LJP5 | 1 | K01 | 72 | hr | 2543 | 3317 | 5734 | 0.5784 | 0.2541 |
| SK-BR-3 | PLX-4720 | 10 | uM | LJP5 | 2 | K01 | 72 | hr | 2543 | 1856 | 5761 | 0.3221 | -0.2344 |
| SK-BR-3 | PLX-4720 | 10 | uM | LJP5 | 3 | K01 | 72 | hr | 2543 | 2465 | 5760 | 0.4279 | -0.0262 |
| SK-BR-3 | Lapatinib | 0.04 | uM | LJP6 | 1 | M24 | 72 | hr | 2543 | 2351 | 5258 | 0.4471 | -0.0723 |
| SK-BR-3 | Lapatinib | 0.04 | uM | LJP6 | 2 | M24 | 72 | hr | 2543 | 2364 | 5438 | 0.4347 | -0.0646 |
| SK-BR-3 | Lapatinib | 0.04 | uM | LJP6 | 3 | M24 | 72 | hr | 2543 | 2288 | 5557 | 0.4117 | -0.0896 |
| SK-BR-3 | Lapatinib | 0.12 | uM | LJP6 | 1 | M23 | 72 | hr | 2543 | 2401 | 5258 | 0.4566 | -0.0535 |
| SK-BR-3 | Lapatinib | 0.12 | uM | LJP6 | 2 | M23 | 72 | hr | 2543 | 2358 | 5438 | 0.4336 | -0.0667 |
| SK-BR-3 | Lapatinib | 0.12 | uM | LJP6 | 3 | M23 | 72 | hr | 2543 | 2130 | 5557 | 0.3833 | -0.1456 |
| SK-BR-3 | Lapatinib | 0.37 | uM | LJP6 | 1 | M22 | 72 | hr | 2543 | 2115 | 5258 | 0.4022 | -0.1614 |
| SK-BR-3 | Lapatinib | 0.37 | uM | LJP6 | 2 | M22 | 72 | hr | 2543 | 2270 | 5438 | 0.4174 | -0.0986 |
| SK-BR-3 | Lapatinib | 0.37 | uM | LJP6 | 3 | M22 | 72 | hr | 2543 | 2173 | 5557 | 0.3910 | -0.1303 |
| SK-BR-3 | Lapatinib | 1.11 | uM | LJP6 | 1 | M21 | 72 | hr | 2543 | 2150 | 5258 | 0.4088 | -0.1482 |
| SK-BR-3 | Lapatinib | 1.11 | uM | LJP6 | 2 | M21 | 72 | hr | 2543 | 2196 | 5438 | 0.4038 | -0.1254 |
| SK-BR-3 | Lapatinib | 1.11 | uM | LJP6 | 3 | M21 | 72 | hr | 2543 | 2134 | 5557 | 0.3840 | -0.1442 |
| SK-BR-3 | Lapatinib | 3.33 | uM | LJP6 | 1 | M20 | 72 | hr | 2543 | 1968 | 5258 | 0.3742 | -0.2171 |
| SK-BR-3 | Lapatinib | 3.33 | uM | LJP6 | 2 | M20 | 72 | hr | 2543 | 2192 | 5438 | 0.4031 | -0.1269 |
| SK-BR-3 | Lapatinib | 3.33 | uM | LJP6 | 3 | M20 | 72 | hr | 2543 | 2341 | 5557 | 0.4212 | -0.0709 |
| SK-BR-3 | Lapatinib | 10 | uM | LJP6 | 1 | M19 | 72 | hr | 2543 | 2588 | 5258 | 0.4921 | 0.0167 |
| SK-BR-3 | Lapatinib | 10 | uM | LJP6 | 2 | M19 | 72 | hr | 2543 | 2887 | 5438 | 0.5309 | 0.1225 |
| SK-BR-3 | Lapatinib | 10 | uM | LJP6 | 3 | M19 | 72 | hr | 2543 | 2997 | 5557 | 0.5393 | 0.1566 |