LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T SNS-032
0.12
uM
LJP6
 3
H17
 72
hr
 765 421 3066 0.1373 -0.2579
Hs 578T CGP60474
0.37
uM
LJP6
 3
G04
 72
hr
 765 435 3066 0.1419 -0.2457
Hs 578T Sirolimus
0.12
uM
LJP6
 3
L17
 72
hr
 765 1938 3066 0.6321 0.5906
Hs 578T Dasatinib
0.37
uM
LJP6
 3
I04
 72
hr
 765 502 3066 0.1637 -0.1897
Hs 578T NVP-TAE684
3.33
uM
LJP6
 3
K14
 72
hr
 765 792 3066 0.2583 0.0174
Hs 578T KIN001-043
0.12
uM
LJP6
 3
C11
 72
hr
 765 3173 3066 1.0349 1.0346
Hs 578T PD173074
0.12
uM
LJP6
 3
I11
 72
hr
 765 2277 3066 0.7427 0.7239
Hs 578T CGP60474
10
uM
LJP6
 3
G01
 72
hr
 765 263 3066 0.0858 -0.4133
Hs 578T BI-2536
0.12
uM
LJP6
 3
D17
 72
hr
 765 463 3066 0.1510 -0.2218
Hs 578T A443654
10
uM
LJP6
 3
I19
 72
hr
 765 247 3066 0.0806 -0.4314
Hs 578T R406
0.12
uM
LJP6
 3
C17
 72
hr
 765 2777 3066 0.9057 0.9035
Hs 578T Imatinib
10
uM
LJP6
 3
N13
 72
hr
 765 3368 3066 1.0985 1.0961
Hs 578T Imatinib
1.11
uM
LJP6
 3
N15
 72
hr
 765 3284 3066 1.0711 1.0698
Hs 578T AT-7519
1.11
uM
LJP6
 3
K03
 72
hr
 765 411 3066 0.1341 -0.2667
Hs 578T AT-7519
0.04
uM
LJP6
 3
K06
 72
hr
 765 2983 3066 0.9729 0.9728
Hs 578T ZSTK474
1.11
uM
LJP6
 3
M15
 72
hr
 765 1296 3066 0.4227 0.3011
Hs 578T R406
1.11
uM
LJP6
 3
C15
 72
hr
 765 2327 3066 0.7590 0.7427
Hs 578T AT-7519
0.12
uM
LJP6
 3
K05
 72
hr
 765 2246 3066 0.7326 0.7122
Hs 578T CGP60474
3.33
uM
LJP6
 3
G02
 72
hr
 765 356 3066 0.1161 -0.3175
Hs 578T AT-7519
0.37
uM
LJP6
 3
K04
 72
hr
 765 475 3066 0.1549 -0.2118
Hs 578T Dasatinib
3.33
uM
LJP6
 3
I02
 72
hr
 765 463 3066 0.1510 -0.2218
Hs 578T AT-7519
3.33
uM
LJP6
 3
K02
 72
hr
 765 333 3066 0.1086 -0.3399
Hs 578T AT-7519
10
uM
LJP6
 3
K01
 72
hr
 765 401 3066 0.1308 -0.2757
Hs 578T Afatinib
3.33
uM
LJP6
 3
G20
 72
hr
 765 2638 3066 0.8604 0.8554
Hs 578T Afatinib
1.11
uM
LJP6
 3
G21
 72
hr
 765 2657 3066 0.8666 0.8620