LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | Withaferin A | 10 | uM | LJP6 | 1 | G13 | 72 | hr | 765 | 394 | 3143 | 0.1253 | -0.2778 |
| MCF 10A | WZ3105 | 3.33 | uM | LJP5 | 3 | D20 | 72 | hr | 1694 | 394 | 11168 | 0.0353 | -0.4150 |
| Hs 578T | Buparlisib | 3.33 | uM | LJP5 | 3 | H02 | 72 | hr | 765 | 395 | 3152 | 0.1253 | -0.2765 |
| BT-20 | SNS-032 | 1.11 | uM | LJP6 | 1 | H15 | 72 | hr | 1334 | 395 | 3955 | 0.0999 | -0.5401 |
| Hs 578T | Geldanamycin | 10 | uM | LJP5 | 1 | O01 | 72 | hr | 765 | 396 | 3140 | 0.1261 | -0.2762 |
| BT-20 | CGP60474 | 1.11 | uM | LJP6 | 3 | G03 | 72 | hr | 1334 | 396 | 3921 | 0.1010 | -0.5423 |
| Hs 578T | JW-7-24-1 | 10 | uM | LJP6 | 2 | B19 | 72 | hr | 765 | 396 | 3095 | 0.1279 | -0.2786 |
| Hs 578T | CGP60474 | 1.11 | uM | LJP5 | 2 | F03 | 72 | hr | 765 | 396 | 3151 | 0.1257 | -0.2756 |
| Hs 578T | SNS-032 | 0.12 | uM | LJP6 | 1 | H17 | 72 | hr | 765 | 397 | 3143 | 0.1263 | -0.2751 |
| Hs 578T | SNS-032 | 10 | uM | LJP6 | 3 | H13 | 72 | hr | 765 | 397 | 3066 | 0.1295 | -0.2793 |
| Hs 578T | CGP60474 | 1.11 | uM | LJP6 | 3 | G03 | 72 | hr | 765 | 398 | 3066 | 0.1298 | -0.2784 |
| Hs 578T | Dasatinib | 3.33 | uM | LJP6 | 1 | I02 | 72 | hr | 765 | 398 | 3143 | 0.1266 | -0.2742 |
| Hs 578T | Alvocidib | 3.33 | uM | LJP6 | 3 | A14 | 72 | hr | 765 | 398 | 3066 | 0.1298 | -0.2784 |
| Hs 578T | WZ3105 | 3.33 | uM | LJP5 | 1 | D20 | 72 | hr | 765 | 398 | 3140 | 0.1267 | -0.2744 |
| MCF7 | CGP60474 | 3.33 | uM | LJP5 | 3 | F02 | 72 | hr | 1389 | 398 | 6038 | 0.0659 | -0.4454 |
| Hs 578T | Alvocidib | 0.37 | uM | LJP6 | 3 | A16 | 72 | hr | 765 | 399 | 3066 | 0.1301 | -0.2775 |
| Hs 578T | CGP60474 | 1.11 | uM | LJP6 | 1 | G03 | 72 | hr | 765 | 399 | 3143 | 0.1269 | -0.2733 |
| Hs 578T | PHA-665752 | 10 | uM | LJP5 | 2 | F13 | 72 | hr | 765 | 399 | 3151 | 0.1266 | -0.2729 |
| MCF 10A | CGP60474 | 0.37 | uM | LJP6 | 3 | G04 | 72 | hr | 1694 | 400 | 11121 | 0.0360 | -0.4124 |
| Hs 578T | CGP60474 | 3.33 | uM | LJP5 | 2 | F02 | 72 | hr | 765 | 401 | 3151 | 0.1272 | -0.2711 |
| Hs 578T | AT-7519 | 10 | uM | LJP6 | 3 | K01 | 72 | hr | 765 | 401 | 3066 | 0.1308 | -0.2757 |
| Hs 578T | PHA-793887 | 10 | uM | LJP6 | 3 | E19 | 72 | hr | 765 | 401 | 3066 | 0.1308 | -0.2757 |
| BT-20 | SNS-032 | 1.11 | uM | LJP6 | 2 | H15 | 72 | hr | 1334 | 401 | 3899 | 0.1028 | -0.5404 |
| BT-20 | SNS-032 | 3.33 | uM | LJP6 | 3 | H14 | 72 | hr | 1334 | 401 | 3921 | 0.1023 | -0.5385 |
| MCF 10A | Withaferin A | 3.33 | uM | LJP6 | 1 | G14 | 72 | hr | 1694 | 401 | 11220 | 0.0357 | -0.4104 |