LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 PLX-4720
0.04
uM
LJP5
 1
K06
 72
hr
 1389 6143 5772 1.0642 1.0615
MCF7 Tozasertib
0.04
uM
LJP5
 1
B18
 72
hr
 1389 1596 5772 0.2765 0.0699
MCF7 Tozasertib
0.04
uM
LJP5
 3
B18
 72
hr
 1389 1524 6038 0.2524 0.0447
MCF7 GW843682X
0.04
uM
LJP6
 1
B18
 72
hr
 1389 4095 5147 0.7956 0.7721
MCF7 GW843682X
0.04
uM
LJP6
 2
B18
 72
hr
 1389 5070 5447 0.9306 0.9284
MCF7 AZD7762
0.04
uM
LJP6
 2
L06
 72
hr
 1389 2012 5447 0.3693 0.2067
MCF7 GW843682X
0.04
uM
LJP6
 3
B18
 72
hr
 1389 4520 5740 0.7874 0.7796
MCF7 Sigma A6730
0.04
uM
LJP5
 1
B24
 72
hr
 1389 4210 5772 0.7293 0.7153
MCF7 Seliciclib
0.04
uM
LJP5
 3
J06
 72
hr
 1389 6077 6038 1.0064 1.0060
MCF7 NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 1389 3856 5147 0.7492 0.7166
MCF7 Torin1
0.04
uM
LJP6
 1
O18
 72
hr
 1389 1824 5147 0.3544 0.1551
MCF7 Sorafenib
0.04
uM
LJP6
 3
B12
 72
hr
 1389 5350 5740 0.9320 0.9323
MCF7 AZD7762
0.04
uM
LJP6
 3
L06
 72
hr
 1389 1929 5740 0.3360 0.1740
MCF7 Imatinib
0.04
uM
LJP6
 1
N18
 72
hr
 1389 5897 5147 1.1457 1.1493
MCF7 Imatinib
0.04
uM
LJP6
 2
N18
 72
hr
 1389 6052 5447 1.1109 1.1096
MCF7 Imatinib
0.04
uM
LJP6
 3
N18
 72
hr
 1389 6001 5740 1.0454 1.0438
MCF7 Sorafenib
0.04
uM
LJP6
 1
B12
 72
hr
 1389 4484 5147 0.8712 0.8592
MCF7 Lapatinib
0.04
uM
LJP6
 3
M24
 72
hr
 1389 4650 5740 0.8100 0.8044
MCF7 Lapatinib
0.04
uM
LJP6
 2
M24
 72
hr
 1389 5016 5447 0.9207 0.9179
MCF7 WZ-4-145
0.04
uM
LJP6
 3
J24
 72
hr
 1389 4359 5740 0.7593 0.7483
MCF7 Sorafenib
0.04
uM
LJP6
 2
B12
 72
hr
 1389 5724 5447 1.0507 1.0508
MCF7 PD173074
0.04
uM
LJP6
 2
I12
 72
hr
 1389 6431 5447 1.1804 1.1756
MCF7 WH-4-025
0.04
uM
LJP5
 1
O12
 72
hr
 1389 5266 5772 0.9123 0.9126
MCF7 Mitoxantrone
0.04
uM
LJP6
 3
C24
 72
hr
 1389 1524 5740 0.2655 0.0463
MCF7 Mitoxantrone
0.04
uM
LJP6
 2
C24
 72
hr
 1389 1585 5447 0.2909 0.0692